Dabalam
Dabalam t1_jboyzd2 wrote
Reply to comment by Serenityprayer69 in Comprehensive review and trial results of upcoming antidepressant Ruoxinlin (ansofaxine) by That-Group-7347
This is a good example of how causality is not always straightforward.
Serotonin reuptake inhibitors do work and work better the better in people with more severe depression symptoms.
However they generally can only be expected to work after around 2-4 weeks where as the serotonin increase is on day 1.
The mechanism isn't exactly "more serotonin = more happy" but that's a bit complex for most people.
Dabalam t1_j7zsmz1 wrote
Reply to comment by MushroomNovaCat in Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (Feb 2023) by basmwklz
I don't think that's accurate. The specific question we're asking is if you control for calories can you achieve the same longevity regardless of diet. Observational studies on people who tend to eat more calorie dense refined food do not control for calorie intake.
Dabalam t1_jd2r7l3 wrote
Reply to comment by z500 in Mountain lion claws Colorado man soaking in hot tub by kk4u
I don't think that thought has passed through the minds of anyone being savagely killed by a wild animal.