DumbDekuKid
DumbDekuKid t1_j035qme wrote
A virus is really just a piece of DNA or RNA surrounded by a carrying container. Retroviruses integrate their genomes into host genomes, other virus genomes can coincidentally be integrated at times. Look at figure 1 in article below for description of retrovirus integration mechanism.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120651/
Our genomes are maybe 10% or more viral dna that no longer has open reading frames/is not expressed.
DumbDekuKid t1_iw67zue wrote
Reply to comment by Indemnity4 in Are we actually running out of Lithium what caused this problem? Also are shifts to renewable energy contributing to the inevitable lithium shortage projected to start by 2025? by Inevitable_Clue9322
The article I posted states Australia obtains majority of Li in world via hard rock mining, as well as South America. China still accounts for >2/3 of lithium refining and has 1/4 of worlds lithium. Australia ships raw to China for refining. China recently purchased a third major lithium mine in South America, and the size of mining operations is in the tens of thousands of acres per mine site. Nothing “interesting” about my choosing China. they refine most, mine a decent amount in Asia, and have purchased a non insignificant portion of South American mines. Compared to the US that has a huge amount of lithium in Maine for example, but the state will not allow mines >3acres, because clearing the land down to the dirt for tens of thousands of acres will obvisouly destroy and displace vast ecosystems. US companies are using fracking tech to get to it. (I like that they are purchasing fracking water and using it, but likely will lead to expansion of fracking) https://uh.edu/news-events/stories/2022-news-articles/may-2022/05172022-lithium.php
DumbDekuKid t1_iw2lqsh wrote
Reply to Are we actually running out of Lithium what caused this problem? Also are shifts to renewable energy contributing to the inevitable lithium shortage projected to start by 2025? by Inevitable_Clue9322
There is no technical shortage of lithium or other rare earth elements in the ground. Plenty down there. Getting it is not like mining for coal. There are no giant chunks of ore to be placed into a cart. Instead of digging a coal mine, to get the lithium and rare earth elements, might as well just destroy the entire mountain and pump out all the ground water! China is cool with destroying an entire ecosystem, US is less comfortable with the intensive and environmentally hazardous lithium mining options. Also, both major methods are time consuming and cost prohibitive. (Although there are plans to do it in North America soon) Plans to use fracking technologies to get to it as well. google pictures of lithium mines and lithium fields and you will see what I mean. Of course increased demand for products will affect shortages. Hopefully new mining techniques will improve the process and minimize environmental hazards, but you can’t mine without damaging the environment and nearby ecosystems. Here is a decent description of lithium mining methods: https://www.sttsystems.com/solutions/lithium-extraction/
DumbDekuKid t1_ivs8ar2 wrote
Reply to How does our body's immune system distinguish between pathogenic microorganisms and commensal? by blue_sloth999
Commensal microbes are established in gut at and after birth. There is always crosstalk between innate cells and gut microbiome. Homeostasis is established and immune priming (innate immune memory) occurs. If diet, disease, etc alter gut microbiome for a long duration, innate cells may lose healthy primed state. Here are three good places to start reading into details of various molecular mechanisms:
https://www.frontiersin.org/articles/10.3389/fimmu.2020.00282/full
https://www.tandfonline.com/doi/full/10.1080/19490976.2021.1939598
https://www.cell.com/immunity/pdfExtended/S1074-7613(22)00177-7
DumbDekuKid t1_ivfr9jt wrote
Reply to If the Human Genome Project represents a map of the genome of a few individuals, why is this relevant to humans as a whole if everybody has different genetics? by bjardd
DNA from one individual is not used to determine consensus genomes anymore, if ever. Many individuals genomes are sequenced. Go to UCSC genome browser and view the most recent human genome build (hg38). Look at your favorite gene, view SNPs. In any single gene, a few single base pairs will vary. These are mapped to the reference genome. It is also very important to note that if you are a physician for example, and you have your patients genome sequenced by the hospital genomics core, the core needs a reference genome to map the patients sequences to so we can easily see where the reads fall in the complete human genome and if there are any significant mutations (done often for cancer patients). Having even a single human genome, fully annotated, to serve as a reference for mapping new sequences to, is ridiculously useful, because humans aren’t that different.
DumbDekuKid t1_ivde1ae wrote
Reply to In IVF treatment, when an embryo is donated to and carried by someone other than the biological mother, does the carrier have any impact on the child's genetics? by [deleted]
Mothers(carrier) diet has been shown to affect epigenome of fetus in-utero: https://link.springer.com/article/10.1007/s00335-020-09839-z
DumbDekuKid t1_iv5e3m5 wrote
Reply to how does a cell know what it's "body parts" do? I mean how does the golgi apparatus know its function/what to do? by DarkFireGerugex
Structure determines function. The structure of the Golgi apparatus determines its function, like the capacity for retrograde and anterograde vesicle transport. Built within the super structure are a myriad of sensors and regulatory pathways. https://www.frontiersin.org/articles/10.3389/fpls.2020.609516/full
There are also overlapping pathways and direct connections between many of the eukaryotic cell organelles, resulting in “organelle-organelle communication”, allowing the entire cell to function and each organelle to “know” what some others are doing. https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-019-0289-8
DumbDekuKid t1_j038223 wrote
Reply to would freezing eggs to use later reduce the risk of age-related complications like downs syndrome, as opposed to just getting pregnant later in life? by knockdownthewall
Still would have increased risks associated with older mother carrying egg(s) to term from epigenetic inheritance. Although would total risks be reduced, yeah certainly in theory.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557560/