Liztliss

Liztliss t1_iuiu7r1 wrote

Reply to comment by panspal in Eli5 What are the long term consequences of drugs that suppress REM sleep? by muted_Log_454

I think perhaps OP was implying that the lack of REM was likely to have played a role in what led to his death, inability to sleep seemed to be the reason he asked for the drugs in the first place 🤔 it would only worsen his mental state from there, requiring more and more to even just achieve sleep alone, which just isn't enough ☚ī¸

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Liztliss t1_iuipryu wrote

Reply to comment by panspal in Eli5 What are the long term consequences of drugs that suppress REM sleep? by muted_Log_454

From Wikipedia:

"On June 25, 2009, American singer Michael Jackson died of acute propofol and benzodiazepine intoxication at his home on North Carolwood Drive in the Holmby Hills neighborhood of Los Angeles, California."

"On August 28, 2009, the Los Angeles County Department of Medical Examiner-Coroner concluded that Jackson's death was a homicide.[2] Jackson had been administered propofol and anti-anxiety benzodiazepines lorazepam and midazolam by his doctor.[3] Murray was convicted of involuntary manslaughter in November 2011, and was released in 2013 after serving two years of his four-year prison sentence with time off for good behavior."

"Jackson had long suffered from insomnia, and had a history of using drugs in an attempt to help him sleep.[14] Jackson's physician Conrad Murray was present to help Jackson sleep and gave him various drugs including diazepam, ativan, lorazepam and midazolam while monitoring him by his bedside.[13] After several hours and several drug injections, Jackson was still unable to fall asleep, and, according to Murray, was repeatedly asking him for "milk", a term for the powerful sedative propofol, which Jackson had used in the past as a sleep aid. At 10:40 AM, with Jackson still not asleep, Murray relented to his requests and injected him with 25 milligrams of propofol diluted with lidocaine. With Jackson finally asleep, Murray testified that he left his bedside to go to the bathroom, and after returning two minutes later, discovered that Jackson was not breathing and had a weak pulse.“

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