Very rare becasue most of mutations are happening on our somatic cells. My understanding is that there are machenisms protecting us from being too mutated from the respective of evolution...
On top of mutations, the heritable genetic information can be stored in a form of "epigenome", where the DNA got modified (methylation) and pass the modified information to the offspring. During fertalization, 99% of the DNA modifications of the reprodutive cells (sperms and eggs) will be erased, which is called "reprogramming". Again, another machenism protects us from "hyper-mutated". The fertilized eggs must be reset to develop into all types of cells as a fetus. However, 1% of them will escape the reprogramming and passed to the next generations, which means the inforamtion from epigenetics MIGHT be inheritable. We do not have solid evidence abt this yet, but good to have a thought about this.
Ok_Mall7281 t1_j0b1icw wrote
Reply to Will my kids inherit the genetic mutations that I aquire during my lifetime? by RedditScoutBoy
Very rare becasue most of mutations are happening on our somatic cells. My understanding is that there are machenisms protecting us from being too mutated from the respective of evolution...
On top of mutations, the heritable genetic information can be stored in a form of "epigenome", where the DNA got modified (methylation) and pass the modified information to the offspring. During fertalization, 99% of the DNA modifications of the reprodutive cells (sperms and eggs) will be erased, which is called "reprogramming". Again, another machenism protects us from "hyper-mutated". The fertilized eggs must be reset to develop into all types of cells as a fetus. However, 1% of them will escape the reprogramming and passed to the next generations, which means the inforamtion from epigenetics MIGHT be inheritable. We do not have solid evidence abt this yet, but good to have a thought about this.