Proteins are amino acids in chains, not free floating individually. So ONE of the amino and carboxy groups are exposed to solute at either end of a given string of a peptide. The rest are hidden in peptide bonds. Also proteins are in 3D, we have buffers, and a ton of other things.
TheDentateGyrus t1_j9cc41w wrote
Reply to Why are we not acidic? by stronkreddituser
Tons of reasons. But specific to amino acids:
Proteins are amino acids in chains, not free floating individually. So ONE of the amino and carboxy groups are exposed to solute at either end of a given string of a peptide. The rest are hidden in peptide bonds. Also proteins are in 3D, we have buffers, and a ton of other things.