Thomas_the_chemist
Thomas_the_chemist t1_iw6xhjv wrote
Reply to comment by BafangFan in A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice (Nov 2022) by basmwklz
But the temp wasn't that low. 24C is 75F and they went up to 30C which is 86F. Both temps are relatively warm. I wonder why the study didn't move a third group to a colder chamber, like 18C?
Thomas_the_chemist t1_istf5lu wrote
Reply to comment by geirrseach in How do new drugs get invented for diseases etc? How do we know that a very specific combination of chemicals will get rid of a curtain illness? by DemetrioGonz
This is the answer right here.
Edit: I feel like it's worth adding a comment about how big chemical libraries are and how big chemical space is. For the uninitiated, "chemical space" is the number of different molecular structures that can be made. For drug-like molecules, an oft-quoted number is on the order of 10^30 to 10^60 different chemical compounds. This is an astronomically large number; think "number of stars in the known universe" large. For perspective, the largest screening libraries are in the millions of compounds (10^6) and virtual screening libraries are in the billions (10^9), but they're always getting bigger. Finding new drugs is truly an undertaking.
Thomas_the_chemist t1_jcnbfnc wrote
Reply to Looking for a good set of dishes by aiden_asphyxia
We have Heath ceramics and they are hefty and beautiful and I love them. Very solid feeling. I wouldn't recommend microwaving them, they say microwave safe ("just don't microwave a turkey on them") but they do absorb the microwaves so the food doesn't get as warm.