christophersonne

christophersonne t1_j9u8xl5 wrote

There have been very few infections in Humans over the last 25 years (under 1000 confirmed last time I checked), and mostly they happen in places that a flu vaccine isn't widely available or used. So, we really have no idea in a real-world sense.

The problem with H5N1 that could cause serious problems is a mutation/variatnt that would allow for human-to-human transmission , which the current variant doesn't have - so a human-affecting pandemic of H5N1 would be a fundamentally different variant to the strain(s) we know of today.

The mutation needed to H2H transmission may or may not affect the protection afforded by a flu vaccine. Think about how different Covid has been, variant to variant, and with the various vaccines we have.
(tldr: more data required)

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