sparky_1966
sparky_1966 t1_j93e9q0 wrote
Reply to comment by thewizardofosmium in Why does the thyroid use iodine ? by geistererscheinung
Thyroid hormones affect regulation of mitochondria and their metabolism, but through signaling. Iodine isn't directly part of metabolism. That may have been what you meant, just wanted to be clear.
sparky_1966 t1_ja8p8n1 wrote
Reply to comment by fingawkward in Is there a genetic disease where the heterozygote has more severe disease symptoms than the homozygote? by Altranite-
You are correct, heterozygous provides some protection from malaria and homozygous causes sickle cell. The heterozygotes are still not normal and are less healthy than normal people, but the negative pressure from malaria is strong enough that it's a net gain.