If it's a man that said the comment you should laugh too loud and awkwardly to get everyone's attention. Make eye contact with the commenter and hold it while you rip a mean fart. Now go back to what you were doing but every so often turn and waft butt air at them to keep them unsettled. This is a dominance game.

Now if it's a woman who made the comment you should do the exact same thing. You aren't sexist. You treat everyone equally.