LibertyPrimeIsASage t1_jegv36l wrote
Reply to comment by svenx in What is known about pain enhancement? For instance, are there drugs that are the opposite of analgesics? If so, what are they and how do they work with neurons/neurotransmitters? by DollyPartWithOn
Really? I took a training course on giving narcan. They said that if someone is not currently on/addicted to opioids, it should have no perceivable effect on them, so if you have suspicion someone ODed and is unresponsive, give it to them, as worst case scenario it does nothing. I now worth it could make a shock case worse. Obviously this is a niche scenario, but I wonder if that's true.
oxycodone_olga t1_jegyx14 wrote
There are even studies that showed opioid antagonists like naloxone increase pain, by reducing the placebo effect in patients. So the natural endorphine system of the body does certainly play a role in placebo induced analgesia
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