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oxycodone_olga t1_jegyx14 wrote

Reply to comment by LibertyPrimeIsASage in What is known about pain enhancement? For instance, are there drugs that are the opposite of analgesics? If so, what are they and how do they work with neurons/neurotransmitters? by DollyPartWithOn

There are even studies that showed opioid antagonists like naloxone increase pain, by reducing the placebo effect in patients. So the natural endorphine system of the body does certainly play a role in placebo induced analgesia

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