fastspinecho t1_iu5aua4 wrote
Reply to comment by DudoVene in Does the cerebral spinal fluid of people with Alzheimer's have a notably different pH from 'normal' people's? by wrhollin
That doesn't really answer the OP's question.
It's entirely possible that pH is both "stable" (i.e. small standard deviation in normal people) AND significantly different in Alzheimer's.
In fact, the more "stable" it is normal people (i.e. the smaller the standard deviation), the smaller a change needs to be in order to be significantly different in Alzheimer's.
For example, if all healthy people have pH between 7.36 and 7.44, then pH of 7.33 would be evidence of pathology.
That said, I don't believe there is any good evidence that the pH of CSF is significantly in Alzheimer's and controls.
Viewing a single comment thread. View all comments