triffid_boy t1_iw3qo3v wrote
Reply to comment by Chiperoni in How do medical researchers obtain lab animals with diseases like specific forms of cancer which arise spontaneously? Do they raise thousands of apes and hope some eventually develop the disease? by userbrn1
Great explanation. Worth touching on this being a reason that a lot of model animal studies don't always scale well to human.
e.g. P53 knockout mice make lots of tumours, give those mice an antioxidant rich diet and they get fewer tumours. P53 is a major component of the antioxidant pathway, so this shows more about p53 pathway than cancer, really.
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