Submitted by menooby t3_103kyz3 in askscience
SimShade t1_j34e06w wrote
Reply to comment by menooby in Do all humans have the same antigens? Or are the antigens in the body the same for everybody? by menooby
Correct. The reason for some people being seronegative for autoimmunity can be due to the variation in epitopes, or the specific parts of an antigen that are recognized by the immune system. If the immune system does not recognize the specific epitopes on a self-antigen, it may not produce antibodies against it, resulting in a negative test result. Additionally, the presence of autoantibodies does not always indicate the presence of an autoimmune disorder. Some individuals may produce autoantibodies as a result of normal immune system function, and they may not develop any clinical symptoms. Therefore, it is often necessary to confirm a diagnosis of an autoimmune disorder through other means, such as a thorough medical history, physical examination, and additional testing.
menooby OP t1_j34e7cg wrote
Very interesting. Thank you for the knowledge once again
Viewing a single comment thread. View all comments