Viewing a single comment thread. View all comments

LessApplication16 OP t1_iso1osm wrote

Reply to comment by RepulsiveVoid in Eli5 does the effect of a drug persist until it completely leaves your system? by LessApplication16

However my question is specifically does the drug remain in the brain for the 250 days or is it cleared into serum,liver,kidneys etc

  • I’m not looking for answers that imply that it’s a good thing to have the drugs in my brain for that long (basically biased) I am actually looking forward to getting rid of the antipsychotic of my body due to how severe my tardive dyskinesia is
1

bostwickenator t1_iso2lg0 wrote

It will not be sequestered

2

LessApplication16 OP t1_iso2pps wrote

Can you clarify since English isn’t my first language.

1

bostwickenator t1_iso3wcf wrote

Your kidneys and liver don't store things up until they break down like that.

2

LessApplication16 OP t1_iso409k wrote

What about serum?can the drug remain in serum rather than exhibit effects on the brain or is that scientifically invalid?

1

bostwickenator t1_iso4k19 wrote

My understanding is that if the drug can pass the blood brain barrier it will continue to do so.

2

RepulsiveVoid t1_iso2cw8 wrote

The drugs are evenly distributed throughout your entire body. Tho some aren't able to reach your brain due to the blood brain barrier and their apparent effect on the brain is BC the bad things in your body gets fought off / repaired.

Edit: So no, the medicine isn't confined to only your brain.

Edit2: I had similar symptoms from SSRI medication.

1

LessApplication16 OP t1_iso3n5x wrote

Really?because I though that tardive dyskinesia was only caused exclusively by dopamine antagonists a.k.a Antipsychotics,I never knew SSRIs do such a thing

1

RepulsiveVoid t1_iso4oui wrote

I'm not sure why, but I wasn't able to keep my feet still. If I sat down, my feet would start to bounce unless I focused on keeping them still, with led to my hands to start drumming or tapping at the hand rests.

One of the medicines I have now(not SSRI) give me occasional "electric" jolts to my hands, with will cause me to spill any galss or mug I'm holding when the "electricity" reaches my neck. It starts from the lower back and travels up in 2-3 seconds, so usually I'm able to put down anything I have in my hands.

1

LessApplication16 OP t1_isoaykp wrote

That isn’t tardive dyskinesia my friend,I have tardive dyskinesia ,basically I have frequent repetitive eye blinking,and every time I try to talk my tongue pulls out making my speech incomprehensible,also occasionally my whole trunk jerks to the right sometimes. What you have could be akathesia/restlessness ,as for the electric shocks it’s a very common withdrawal effect of psych meds

1

RepulsiveVoid t1_isomoz7 wrote

Oh, yeah, Those are definietly two different things.

Sometimes or mostly they probably are withdrawal or low med-level related, but occassionally I get them even when I've taken my medication as prescribed. I also suspect they are linked to my social anxiety medication as I'm using, unorthodoxically, benzoes designed against epliectic seizures for it.

​

Edit: u/bostwickenator is also to my understanding 100% correct, so +1 to him.

1