Scarcely. This may be true in the most childlike pedestrian sense, but it holds zero water in terms of even the most basic understanding of New World archaeology and anthropology. There simply is no schemata in which we view the mesoamerican civilizations as having anything whatsoever to do with your South American cultures.

They are totally and completely unrelated and while I think they probably did have a notion of one another, it would have been very dim and mitigated through a long and unreliable trading chain of goods that rarely reached one or the other, and for which we have nearly zero archaeological evidence.