95 all the way; don't bother with anything else until you get to I-4.

Source: Lived in Orlando for seven years and made that drive when I was moving from the fucking shithole known as Illinois, stopped for a week to see family in NJ where we're all from on the way down. (For me it was 80 to 287 to my grandmother's. Then it was the Turnpike to the Delaware Memorial Bridge and 95 the whole way from there.)

If you're going to stop for a night, I suggest around Fayetteville NC. Since it's near a major Army base, the hotels aren't too bad on pricing, and the Chinese food at the place we hit for dinner was surprisingly on point (however that was 21 years ago, place may not even exist anymore).

There are not many patrols in any of the states, and tomorrow you should be totally clear to set at least 90 on the cruise control. Watch out for construction zones, of course...