The only way to get over your fear is to get out and do it. I grew up near Boston—when I first learned to drive, I was stupidly nervous almost all of time I was on the road. My first trips into the city on my own in a car were terrifying, but the more I did it the more I became comfortable. Eventually when I came to New York, it was no problem. If anything New York (or at least Manhattan) was easier because of the grid layout.

My big piece of advice is to be vigilant for those not in a car, such as pedestrians and bikers. Take extra care to check your mirrors and blind spots.

Edit: one thing, especially on those left turns, is to never let other drivers or being self-conscious pressure you into making a split second decision out of fear. If you don’t feel like you can make a safe move, don’t just because someone is honking at you. That’s how mistakes happen.