>be in Graduate Hospital and need to get to Temple's North Philly campus, despite not knowing how to get there, but knowing that you're in the southern half of the city

>look at skyline, see City Hall ahead of you and to the right

>think "ok I'm looking north, City Hall is to the east, so I'm southwest of it"

>think "I need to travel east a bit, and then North till I hit Temple's campus

works really well if you know the grid too