2nd Street is fine from spring garden to girard, super gentrified, if you are south of spring garden im not as familiar. There isnt much south other than one condo building and crazy intersections.

Many nightlife places to checkout, standard tap has been around forever, the abbaye over on 3rd, urban village brewery up towards girard, heritage, etc.

I would be aware of your surroundings at the 95 overpass at spring garden station, sometimes people hangout there. Also for spring garden station itself, exit on the south side where the entrance is. The north side exit has a blind uturn that people relieve themselves or hangout in and you can't see them from the top of the stairs.