Is reality exists then truth exists, so it depends on whether you (the observer) thinks reality exists or not.

While uncertainty in physics is a fact, it could be that this reveals more about the state of human knowledge than it does what’s seen as uncertain.

The act of observing at the smallest of scales is accomplished by interfering, so it very may well be that the interference is what is impacting results. I won’t say what is possible or impossible with regards to future technology because what we have today was considered impossible not that long ago. These dilemmas currently do not have solutions.