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gospdrcr000 t1_ixz674c wrote

I like that there doing a study about it, but i thought this was already a well established known fact.

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tornpentacle t1_ixzryml wrote

Well, OP didn't use the actual title of the paper. This goes into the chemistry of it. It is very well known that heat decarboxylates cannabinoids. Perhaps not as well known (not popularly, nor in the literature) are the specifics of the chemical changes that occur, which molecular bonds break, what other byproducts are created, etc.

From the abstract:

>In particular, most of the CBDA was converted into CBD at 130 °C for 20 min; this CBD was partially transformed to psychotropic THC isomers via cyclization. In addition to THC isomers, cannabielsoin acid (CBEA) and cannabielsoin (CBE) were also observed as minor oxidative transformed products. Based on structural identification and profiling data, thermal transformation pathways of CBDA are plausibly suggested. The results of decarboxylation of ACBs will provide important information on production of neutral cannabinoids, especially CBD, in Cannabis plants and quality control of Cannabis-based products in pharmaceutical and cosmetic industries.

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AlpacaM4n t1_ixzchf6 wrote

That is like 90+% of studies, known in practice vs proven

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SirHammyTheGreat t1_ixzcvl8 wrote

This is just sort of confirming the first step in making edibles, but they did it with CBDA -> CBD instead of D9-THC -> THC, right?

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tornpentacle t1_ixzw8po wrote

No. Read the abstract at the very least. OP wrote this title and it completely ignores what the researchers actually studied.

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Bulky-Pool-5180 t1_ixzvjz4 wrote

They have to continually fund the studies in order to keep the people thinking products are in development rather than available.

Then there are the corporate media choking themselves on the words SMOKING POT every instance they mention the plant.

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tornpentacle t1_ixzw4ra wrote

Your comment gives away the fact that you did not read the study...

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Bulky-Pool-5180 t1_ixzx24m wrote

No. Why would I?

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tornpentacle t1_iy03nuu wrote

Well, because you're commenting, and the comments section is for people who have things to say that are relevant to the content posted.

Generally not desiring to out yourself as a person who speaks without thinking might be another reason.

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Bulky-Pool-5180 t1_iy3uh1y wrote

Comments sections are for everyone. Speaking without thinking and commenting without reading the article are unrelated. None of this is relevant.

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HairyBull t1_ixz8a3m wrote

Doing the important science!

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hyerstandardsmedia t1_ixzo3vb wrote

Decarb your nugs before you make your brownies or they'll upset your stomach

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Lauwarmes t1_iy0xyzk wrote

there are two ways: waiting a long time (won't decarb fully) or putting it in the oven on a parchment paper. the decarboxylation happens at a higher temp for CBD than for THC the temperature is not well defined as it takes longer at lower temperatures. 100 °C (212 degrees of Freedom unit) for an hour is a safe starting point. beware that oven temperature regulators are usually very simple and might overshoot the set temperature depending on heating rate and device used. so staying way below 200 °C and preheating is recommendable to not alter the flavor profile too much and prevent further decomposition.

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Rhigerarasv t1_iy29geh wrote

OSU study shows that CBDA and CBGA prevented human infection and replication of covid virus.

While this study says to decarb, keeping the cannabinoids in form of CBDA / CBGA would be beneficial in this respect, no?

https://today.oregonstate.edu/news/oregon-state-research-shows-hemp-compounds-prevent-coronavirus-entering-human-cells

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TeddyBadgr t1_ixzdlsb wrote

How old is this study? Any of us working in Cannabis R&D/processing/production are aware of this, and have been for a hot minute. Sorry OP maybe this post was for the layman, but this is pretty well known by the relevant parties.

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tornpentacle t1_ixzshek wrote

Perhaps you should read the paper and not just the title (which was written by OP). This is new information.

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Bulky-Pool-5180 t1_ixzv3nq wrote

It is a myth that decarboxylation takes place naturally, and Cannabis is not a "container" of THC.

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tornpentacle t1_ixzvrap wrote

That is simply untrue. Decarboxylation also occurs at room temperature, but the reaction takes place at a much lower rate. Any tested sample of dried cannabis flower will contain the cannabinoid acids and smaller amounts of the decarboxylated cannabinoids. For a ready proof that you can find and choose yourself, look at the lab test results of any online hemp store—any cannabis flower invariably contains decarboxylated cannabinoids (because that's how physics works... relatively unstable chemical groups are prone to decomposition).

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Bulky-Pool-5180 t1_iy01b2h wrote

You are equating dried plant material to Cannabis flower. Cannabis flower is wet-weight by default...not dried. Decarboxylation is Temperature, Humidity and Light effected.

Technically...Marijuana is Cannabis' low-thc cousin.

0

Ok_Tree6772 t1_iy2wcf8 wrote

I grow a new batch every 4 months or so and can vouch that fresh buds are more intense but less calming. After several months stored properly it just doesn't do it for me and it all gets turned into joints for outings.

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mobyhead1 t1_ixzaftt wrote

Alternative medicine once again on its way to becoming medicine. Because if natural Salicylic acid were still somehow better for you we would still be chewing Willow bark instead of taking two aspirin.

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irrelevantastic t1_ixzpkq7 wrote

ASA was manufactured for proprietary purposes, and adding the acetyl group actually made it toxic, hence the increased risk of Reye's syndrome that isn't seen in those taking willow bark as a febrifuge.

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tornpentacle t1_ixztkiq wrote

[Edit added in brackets to beginning: you have posted dangerous misinformation. In fact, China now legally mandates all willow products to be accompanied by messaging warning against administration to children after a series of Reye's Syndrome cases in 2009 due to administration of willow bark to children.]

Original comment, as it appeared initially, follows below underscores. Please note that the first clause of the first sentence should now read, "That is not correct, and".


Not sure about the validity of this, but in practice this is dangerous without additional information. People will come away from this thing salicylic acid is safer in general, because your comment doesn't specify that chewing bark provides only a very small amount of the stuff. But extracts of willow bark cause a relatively large number of toxicity cases because it is seen as natural and healthy. People use the oil on large patches of their skin, thinking it's fine because it's topical and won't enter the bloodstream, but it gets absorbed and can very easily reach toxic levels.

The same thing happens with methyl salicylate, aka wintergreen oil. There are far too many toxicity cases because of people's insane belief that natural means safe.

To those people, I say: eat a couple poppy pods and see how that works out for you. (Obviously I'm not suggesting anyone do this, but for liability's sake I think it needs to be clarified that it was only said to make a point. If you eat poppy pods, you will almost certainly die.)

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