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irrelevantastic t1_ixzpkq7 wrote

Reply to comment by mobyhead1 in Decarboxylation of cannabidiolic acid (CBDA) is an important step for efficient production of the active pharmaceutical component cannabidiol (CBD) in Cannabis species. Acidic cannabinoids (ACBs) can be easily transformed into neutral cannabinoids via loss of carbon dioxide when exposed to heat by The_R3venant

ASA was manufactured for proprietary purposes, and adding the acetyl group actually made it toxic, hence the increased risk of Reye's syndrome that isn't seen in those taking willow bark as a febrifuge.

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tornpentacle t1_ixztkiq wrote

[Edit added in brackets to beginning: you have posted dangerous misinformation. In fact, China now legally mandates all willow products to be accompanied by messaging warning against administration to children after a series of Reye's Syndrome cases in 2009 due to administration of willow bark to children.]

Original comment, as it appeared initially, follows below underscores. Please note that the first clause of the first sentence should now read, "That is not correct, and".

Not sure about the validity of this, but in practice this is dangerous without additional information. People will come away from this thing salicylic acid is safer in general, because your comment doesn't specify that chewing bark provides only a very small amount of the stuff. But extracts of willow bark cause a relatively large number of toxicity cases because it is seen as natural and healthy. People use the oil on large patches of their skin, thinking it's fine because it's topical and won't enter the bloodstream, but it gets absorbed and can very easily reach toxic levels.

The same thing happens with methyl salicylate, aka wintergreen oil. There are far too many toxicity cases because of people's insane belief that natural means safe.

To those people, I say: eat a couple poppy pods and see how that works out for you. (Obviously I'm not suggesting anyone do this, but for liability's sake I think it needs to be clarified that it was only said to make a point. If you eat poppy pods, you will almost certainly die.)

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