Our laws of physics are based on our current understanding of the universe. They used to think the Earth was flat. The best science at the time believed it was this way.

Further, we already know we have some pretty big unknowns, for instance, dark matter and dark energy exists solely to fill a gap in our understanding. And we also know we have some big assumptions that the same laws of physics apply everywhere.

For the applications we typically use these assumptions for, stuff we’re doing around Earth and the Sol system it’s fine. For principles of the universe these assumptions and unknowns are a much bigger deal.