To me, they've best burgers are always homemade.

Outside that, Bairs has probably a couple dozen different ways they top their burgers foe some variety. If you just want to taste the meat, I'd go with w.f. Cody's on Sunshine.

For an old time dinner burger, ots a bit out of town but Kad-E-korner deli between fair grove and springdield on H (north glenstone) has a good burger and fresh cut curly fries that always hit the spot.