They would love to deliver it the way that is most likely to be done correctly and most welcomed by the patients and doctors. That’s oral pills. They’ve come up with clever ways to do slow release that is protected from the stomach but absorbed in the intestines, for some drugs. Then it has to be protected from degrading enzymes so it stays in the blood or liver at the right level the longest before another pill is needed. Then the degradation products have to be harmless.

When a drug can’t be designed for this, you end up with things like multiple pills per day, or injections, or liquids, or patches, or nasal sprays, or rectal suppositories. Sometimes a patch is best because it can be slow release.

It depends on the drug. They are going to already know what delivery will likely work without further modification. For example, oral delivery is going to need to survive the stomach and get absorbed. Timing of release and half-life in the blood stream also factor into delivery method. They take these into account when deciding the best way to deliver the drug. Target organ also matters.

Honestly, the only movie I saw in theaters was The Fifth Element.

I used to go to movies every week. The pandemic kind of killed that.

In the before times (pre-Covid), it was in April. It might still be.

I stumbled upon it at Anime Boston a few years ago and ended up watching the whole thing instead of just taking a few minutes to rest my feet. Sweet movie.

The big one is that diet soda has a lot of phosphorus in it. If you drink too much, that can suck calcium out of your bones and not just weaken your bones but also encourage kidney stones.

After Star Wars The Phantom Menace.

“That cute little kid becomes such an asshole.”

It isn’t countries doing this. It is companies. Just because a company has access to a resource, and someone in the same country wants that resource, it doesn’t mean they have arranged to sell to the closer buyer. They may have a better deal to sell to someone in another country. The same goes for the buyer. They might have a better seller lined up elsewhere.

It sounds inefficient, but not necessarily, depending on how the supply lines are set up.

I really enjoyed seeing The Fifth Element on the big screen.

I think that’s the only movie I saw in an actual theater this year.

No, I mean that historically, there is way less need to read on a farm than in a law office. I’m thinking 1820, not 2020.

This. My four year old was a solid speaker long before he could read the language.

Imagine if no one bothered to teach him. Or he grew up on a farm with parents who grew up on a farm…

I'm still confused exactly what 'heat' is. What is heat?