I can’t really add much to this response as it pretty well covers it all. I can point you to Jackson Laboratories where you can see the phylogenic tree of how hundreds of different mouse models arose from a handful. It’s a fun rabbit hole if you’re interested in animal research.
It’s not just disease models. You can compare genes associated with physical activity by having C3H/HeJ and C57/LJ mice in cages with wheels. The C57s will run up to 20km a day, compared to 2km. It’s amazing how far we’ve come in research methods; and they’re still improving and evolving.
LogSouth2717 t1_iw5nrhy wrote
Reply to comment by Chiperoni in How do medical researchers obtain lab animals with diseases like specific forms of cancer which arise spontaneously? Do they raise thousands of apes and hope some eventually develop the disease? by userbrn1
I can’t really add much to this response as it pretty well covers it all. I can point you to Jackson Laboratories where you can see the phylogenic tree of how hundreds of different mouse models arose from a handful. It’s a fun rabbit hole if you’re interested in animal research.
It’s not just disease models. You can compare genes associated with physical activity by having C3H/HeJ and C57/LJ mice in cages with wheels. The C57s will run up to 20km a day, compared to 2km. It’s amazing how far we’ve come in research methods; and they’re still improving and evolving.