Thank you for the addition, this is something that should be brought in the spotlight. Appreciated.

The presence of neurofibrillary tangles and beta amyloid plaques (which recently have sparked controversy). Lead to the degradation of the cortex of the brain. Dementia is the term used to describe impaired cognitive status. The severity of the disease is typically generally attributed to the amount of neurofibrillary tangles. A decrease in the neurotransmitter acetylcholine is present as well. Drugs that increase this neurotransmitter help with symptomatic management but do not slow the profession of the disease.