The alignment problem is not easy, but also not without hope.

David Sinclair, one of the main authors of this study, wrote a book called Lifespan which describes the epigenome theory of aging in more detail.

I recommend it- Sinclair argues persuasively that senescence should be thought of as not just a disease, but as the most important disease, since it leads to so many others- and he outlines a lot of promising-looking lines of research that may one day lead to effective mitigation or a cure.

Note, though, that while Sinclair seems pretty well-respected by other researchers, he does also have some pretty large financial stakes in anti-aging supplement companies, which could be biasing his work.