dkysh
dkysh t1_j7fq4mw wrote
Reply to comment by snappedscissors in Sound Waves Trigger Anti-Cancer Immune Responses in Mice by dissolutewastrel
I suspect these "physical disturbance" techniques could cause part of the cells on the principal tumor to detach, becoming potential metastases.
"Conventional" cancer treatments either make sure that the cell commits suicide/the immune system kills it, or remove the tumor from the body.
dkysh t1_j50ssc6 wrote
Reply to comment by JFSOCC in Given that reproduction is difficult or impossible when both animals have different numbers of chromosomes, how did so many species evolve to have so many different numbers of them? by MercurioLeCher
If we were bacteria, yeah, sure. But we are extremely complicated multicellular organisms. A whole genome trisomy screws up the balance of gene expression to such an extreme that most trisomies are simply lethal and never observed (they end up in miscarriage).
A gene fusion is a less drastic event, where 2 chromosomes happen to be connected, but the genetic load is identical.
dkysh t1_j50geul wrote
Reply to comment by VictoriousEgret in Given that reproduction is difficult or impossible when both animals have different numbers of chromosomes, how did so many species evolve to have so many different numbers of them? by MercurioLeCher
Building a "reference genome" for a species from scratch is a whole field of science.
When people do "normal sequencing", the genome is broken into an infinity of small pieces. The genome of chimpanzees, gorillas, and orangutans fit so well the human genome, that scientists usually use the human reference genome to study great apes.
Some scientists compared both the human and the chimpanzee reference genomes built independently from scratch, and they found just minimal differences. All this shows that the human chr2 and the great ape chr2a and 2b are almost identical in they just happened to fuse in proto-humans sometime in the last 6 million years.
dkysh t1_j506qis wrote
Reply to comment by fruticosa in Given that reproduction is difficult or impossible when both animals have different numbers of chromosomes, how did so many species evolve to have so many different numbers of them? by MercurioLeCher
Another (close) example: Human's chromosome 2 is the result of the fusion of other 2 smaller chromosomes present in all other great apes, chromosomes 2a and 2b.
The content of chr2a+2b is almost identical to human's chr2, even with genes following the same order. This makes them much more compatible and probable to recombine and produce viable offspring.
dkysh t1_j0aragh wrote
Reply to comment by Snapple207 in Will my kids inherit the genetic mutations that I aquire during my lifetime? by RedditScoutBoy
The sperm cells themselves are very short-lived. However, they do originate from spermatogonial stem cells that keep on replicating theough all your life.
In a cartoon, these stem cells divide into two cells. One of these daughter cells (cell A) keeps being a stem cell and the other not (cell B), begining a chain of divisions into further daughter cells that end up being a bunch of sperm.
New mutations appearing on cell B will only be found in one "round" of sperm. Mutations appearing in cell A are there to stay in all future rounds.
dkysh t1_iuy6std wrote
https://en.wikipedia.org/wiki/Paranthropus_boisei#Postcranium
> Unlike P. robustus, the arm bones of OH 80 are heavily built, and the elbow joint shows similarities to that of modern gibbons and orangutans. This could either indicate that P. boisei used a combination of terrestrial walking as well as suspensory behaviour, or was completely bipedal but retained an ape-like upper body condition from some ancestor species due to a lack of selective pressure to lose them.
Although this "suspensory behaviour" doesn't need to be brachiation, Gibbons have exceptional upper body strength as an adaptation to brachiation as a locomotion mode: https://onlinelibrary.wiley.com/doi/full/10.1111/j.1469-7580.2009.01109.x
So, no idea, but could be possible. Depends on your definition of strength.
dkysh t1_iuhur1l wrote
Reply to comment by Isaaker12 in [homemade] Basque Cheesecake by Jazzlike-Republic-58
Es un invento reciente de un cocinero vasco. Está crudita por dentro y quemada por fuera.
dkysh t1_itmg6u8 wrote
Reply to comment by Bucklehairy in "All Spaniards, we discovered, knew two English expressions. One was ‘OK, baby,’ the other was a word used by the Barcelona whores in their dealings with English sailors, and I am afraid the compositors would not print it." by SlitchBap
Or "x pesetas/dollars, suck and fuck".
dkysh t1_jdr6zli wrote
Reply to comment by ChilindriPizza in Any type of hormonal contraceptive may increase risk of breast cancer: according to an analysis of data by researchers at Oxford, progestogen-only hormonal contraceptives may increase breast cancer risk by 20-30%; the use of combined contraceptives may also slightly increase breast cancer risk. by aiaaidan
> These excess risks must, however, be viewed in the context of the well-established benefits of contraceptive use in women's reproductive years.’