A bit indirect, but some forms of achondroplasia are so severe that homozygotes are incompatible with live birth, and thus heterozygous (or homozygous would type) are the only observed.
A better example: ABO blood types in terms of blood contaminagion (whether available acceptable blood types, or maternal-fetal hemolytic anemia). Diversity of heterozygous actually works against a “phenotype” of immune acceptance.
zk3033 t1_ja8ba9s wrote
Reply to Is there a genetic disease where the heterozygote has more severe disease symptoms than the homozygote? by Altranite-
A bit indirect, but some forms of achondroplasia are so severe that homozygotes are incompatible with live birth, and thus heterozygous (or homozygous would type) are the only observed.
A better example: ABO blood types in terms of blood contaminagion (whether available acceptable blood types, or maternal-fetal hemolytic anemia). Diversity of heterozygous actually works against a “phenotype” of immune acceptance.