nowlistenhereboy t1_irxg5jb wrote
Reply to comment by thehazer in Insulin modulates emotional behavior through a serotonin-dependent mechanism - impaired insulin-sensitivity in these DR 5-HT neurons is critical for the development of T2D-associated mood disorders. by Meatrition
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671104/
It's possible to have insulin resistance as a type 1 diabetic although not every type 1 diabetic has insulin resistance. It's partially genetic. Also partially depends on your diet. If a type 1 diabetic eats excessive calories, they will have to self administer more insulin, and will obviously incur insulin resistance in response to that extra insulin just like a type 2 diabetic does. There is also some effect in the fact that DM1 patients administer insulin into their fat, which seems to result in insulin resistance in the body (periphery) but less so in the core (liver and presumably other organs like the brain too).
Mando92MG t1_iryb5yg wrote
I'm a type 1 diabetic and when I was a teenager and young adult I ended up developing such a high degree of resistance (my ratio was 1 unit for every 3g of carbs at the worst) that I nearly made myself into a type 2 diabetic as well. Genetics has some role to play in that but mostly it was me being a idiot. I got diagnosed at 22 months and by the time I turned 14 I had decided "F*** it" and just started doing whatever I wanted. However by the time I turned 21 after being hospitalized over a dozen times in like 7 years and my kidneys starting to fail. I finally got my s*** back together and started taking care of my self. Now a decade later I've somehow managed to come back from the edge, no protein in my urine and my insulin tolerance is in the average range for a type 1 my age. I bring it up cause I feel it is anecdotal evidence of the effects of varying resistance. A type 2 that let themselves get to that point would have never gotten themselves back to normal resistance levels again.
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