happysheeple3 t1_isu474m wrote
Reply to comment by Dawrin in Severe COVID-19 may increase the risk for schizophrenia by chrisdh79
I hope we get one that explores a possible risk stratification for serious outcomes from covid-19 with varying intakes of added sugars (sucrose, fructose and high fructose corn syrup)
The average American consumes around 57 pounds of sweeteners per year. Added sugars including sucralose and aspartame have been found to be Pro-inflammatory and could very well take a large part of the blame for the covid-19 "cytokine storms" described in the literature.
>Fructose pathway involved in oxidative stress and inflammation. In the hepatocyte, fructose sugar is rapidly metabolized by KHK, depleting ATP and resulting in uric acid accumulation. Uric acid activates NADPH oxidase with production of ROS, which activates mitochondrial ROS production and stimulates UPR in ER. ER stress may also activate mitochondrial ROS production and vice versa. Moreover, ER stress contributes to progression of hepatic steatosis activating lipogenic genes via PERK, ATF4, and IRE1 and inducing SREBP-1c that increases the activity of ACC and FAS. As a response of excessive oxidative stress, inflammatory and apoptotic pathways are activated through JNK, NFkB, and CHOP, resulting in an increased production of cytokines (IL1ß, TNFa, IL19), which plays an important role in the development of NASH.
greyrobot6 t1_isukecm wrote
Recently started acupuncture for tendinitis in my arm that has been extremely resistant to treatment for ongoing 3 months now. Can’t get past the pain. Dr put me on a keto diet for 2 wks to jumpstart decreasing the inflammation in all of my body due to sugar. The only time I actively put sugar in anything was the 2 tsp in my morning coffee, then water all day. I don’t even have a sweet tooth. But everything else I’ve been consuming has so much added sugar! Products that are labeled light have more added sugar than full fat products. There is so much more, it’s been eye opening and I’m already feeling a difference. This has made me getting Covid as I am right now an even bigger fear.
aelis68 t1_isv1mqk wrote
Interesting. I had issues with my arm pre-CoVID that disappeared after a few months of Vitamin D 10k iu/daily after testing showed I had almost none. I’m convinced that helped me stay CoVID free until finally coming down with it last month.
happysheeple3 t1_isus0ew wrote
I'm so happy to hear a Dr. that's willing to say that! So many of them mindlessly believe what they're taught in school which in many cases is antiquated or outright false information. It warms my heart to hear that!
If you don't partake in marijuana already, try a THC tincture. Make sure it's full spectrum and isn't flavored. I had inflammation which I saw great improvement in when I started. CBD can work too, but it isn't as strong and the effects don't last as long, at least in my personal experience.
If you're easily addicted to things, stick with cbd.
greyrobot6 t1_isutyb0 wrote
Indica every night for sleep. It does help with the pain until I fall asleep as well but the straight CBD tincture hasn’t worked as well for me and being stoned all day isn’t an option for me. I didn’t notice any obvious improvement with the inflammation anyway. The herbs the Dr has me on taste pretty horrendous but have helped considerably already.
happysheeple3 t1_isvq1ib wrote
I take it before bed and I don't ever feel high. It only takes 25mL of the full spectrum tincture to get results. Music will sound a little nicer, but no head rush unless I overdo it with like 75mL.
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