Meh. I hope I’m wrong, but looks like cure of aging is new “fusion energy” and “new battery breakthrough”

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Why do you say that? You Will have a lot of People already retired and most of them without any useful hability. And they wont die. In the long term maybe you can train them again if you revert brain damage But it's unlikely when the coming years are gonna bring up unenployment even without This.

I'm not against it and I hope that it happends But it's gonna be a challenge.

Hell, in my country if you lose your job at 50-55 its already almost imposible to get one... Imagine the ones with 65-90 coming back....

The population would explode exponentially. We need other technologies to work with this first, like being able to build an outer colony. Before Immortality we need Ai to nanny us first lol. Plus this would sharing more money, which elite don't like to do, therefore more poverty. Again we need Ai to create and deploy on its own and bring down costs of development. Hopefully eradicate Capitalism, but again elite won't like that. I'm watching Elysium now ;)

Aren’t many senolytics in human trials like the ones from the Mayo Clinic.

Bezos isn't actually as much of a jerk as many people think he is. Of course being human he's a complicated character and he has done some bad things there's no doubt about that.

>How about posting the text from the article. All I can read is the first paragraph which is pointless.

LIFE EXPECTANCY IN the best-performing countries has been increasing by three months per year every year since the early 1800s. Throughout most of human history, you had a roughly 50–50 chance of making it into your twenties, mainly due to deaths from infectious diseases and accidents. Thanks to medical advances, we’ve gradually found ways to avoid and treat such causes of death; the end result is perhaps humanity’s greatest ever achievement—we’ve literally doubled what it means to be human, increasing lifespans from 40 to 80 years. On the other hand, this has allowed one scourge to rise above all the others to become the world’s largest cause of death: aging.Aging is now responsible for over two-thirds of deaths globally—more than 100,000 people every day.

This is because, counterintuitive though it may sound, the chief risk factor for most of the modern world’s leading killers is the aging process itself: Cancer, heart disease, dementia, and many more health problems become radically more common as we get older. We all know that factors such as smoking, lack of exercise, and poor diet can increase the risk of chronic diseases, but these are relatively minor compared to aging. For instance, having high blood pressure doubles your risk of having a heart attack; being 80 rather than 40 years old multiplies your risk by ten.

As the global population ages, the magnitude of death and suffering caused by aging will only increase.But this isn’t my prediction—apart from being depressing, extrapolating a two-century trend for a further year is hardly groundbreaking. What’s far more exciting is that, in 2023, we may see the first drug that targets the biology of aging itself.Scientists now have a good handle on what causes us to age, biologically speaking: The so-called “hallmarks” of the aging process range from damage to our DNA—the instruction manual within each of our cells—to proteins that misbehave because of alterations to their chemical structure. Most excitingly, we now have ideas of how to treat them.By the end of 2023, it’s likely that one of these ideas will be shown to work in humans.

One strong contender is “senolytics,” a class of treatments that targets aged cells—which biologists call senescent cells—that accumulate in our bodies as we age. These cells seem to drive the aging process—from causing cancers to neurodegeneration—and, conversely, removing them seems to slow it down, and perhaps even reverse it.A 2018 paper showed that in experiments in which mice were given a senolytic cocktail of dasatinib (a cancer drug) and quercetin (a molecule found in colorful fruit and veg), not only did they live longer, but they were at lower risk of diseases including cancer, were less frail (they could run further and faster on the tiny mouse-sized treadmills used in the experiments), and even had thicker, glossier fur than their littermates not given the drugs.

There are more than two dozen companies looking for safe and effective ways to get rid of these senescent cells in people. The biggest is Unity Biotechnology, founded by the Mayo Clinic scientists behind that mouse experiment and with investors including Jeff Bezos, which is trialing a range of senolytic drugs against diseases like macular degeneration (a cause of blindness) and lung fibrosis. There are many approaches under investigation, including small proteins that target senescent cells, vaccines to encourage the immune system to clear them out, and even gene therapy by a company called Oisín Biotechnologies, named after an Irish mythological character who travels to Tir na nÓg, the land of eternal youth.

Senolytics aren’t the only contenders, either: Others currently in human trials include Proclara Biosciences’ protein GAIM, which clears up sticky “amyloid” proteins, or Verve Therapeutics’ gene therapy to reduce cholesterol by modifying a gene called PCSK9. The first true anti-aging medicine will very likely target a specific age-related disease driven by a particular hallmark, rather than aging writ large. But the success of a drug targeting an aspect of aging in clinical trials will allow us to consider this loftier goal in the not-too-distant future.In 2023, early success of these treatments could kickstart the greatest revolution in medicine since the discovery of antibiotics. Rather than going to the doctor when we’re sick and picking off age-related problems like cancer and dementia in their late stages when they’re very hard to fix, we’ll intervene preventively to stop people getting ill in the first place—and, if those treadmill-shredding mice are anything to go by, we’ll reduce frailty and other problems that don’t always elicit a medical diagnosis at the same time.

why would you want to be taller? It correlates with living a shorter life span, anyways it isn’t really an easy task the plates responsible for growth seal into bone, you’d have to break the bone and then somehow make them start dividing again.

Skee-lo has entered chat

When will they make us a baller?

When will they make us a girl who looks good so we can call her?

I think people here are certainly overly optimistic, but there's so much compounding change that nobody really has any idea where we'll be at in twenty years time. We have no idea how a treatment for aging will be discovered or what technology it will require, so how can we even begin to guess how long it will take? Could be five years. A hundred. Never. Nobody knows.

I mean youre bold saying that AGI will come in 2040s. This is ridicolously long time from today.

>We are decades and decades away...

Yes this sub is very much overly optimistic thus I am wary of many of the claims made here, but I'm also wary of people who throw up baseless nonsense like this as well.

Considering that most people, this includes experts, cannot come even close to making accurate future predictions past 5 years or so I immediately tune out when people drop the "maybe in a 100 years" or the "decades and decades" spiel.

It's been said that humans can only make reasonable/feasible predictions in a time span of roughly 3 years, with 5 years being generous.

Anything past that is just wild ass guessing and the reason for that is we have no idea what break throughs can suddenly pop up or what technologies come to fruition that prior predictions didn't account for because we had no way of knowing/expected.

There are just too many unknowns past the 3-5 year mark is what my point is, so speaking so matter-of-factly about things that far out is an absurdity.

How would a world look like where we have AGI but it still takes another 10-20 years to reach LEV?

I'm tired of this argument. Many of the drugs investigated are already very cheap and available (metformin, NMN, fisetin, to name a few popular ones that you can buy easily), and scaling production to the entire population will be immensely more profitable than selling it to a few wealthy people.

Exactly. They said tap water, antibiotics, cars, aeroplanes, personal computers and the internet would be available to everyone too. Last time I checked though, only the richest kings of Europe could afford any of those. What a scam!