My dad had Bladder cancer a bit more than a decade ago. I think he was around 58 at the time he found out. He'd been a daily smoker of cigarettes for most of his life (had quit around 5 years prior) but also a daily toker. His doctors told him he was fine to keep smoking, and actually encouraged it for several reasons (appetite being the main one). Thankfully it never got out of hand, and weirdly they used localized TB to treat it.

95/50ish is my resting BP and I'm a 29 year old man. I used to donate blood and plasma quite a lot in my early twenties and twice my BP was too low to donate, so I basically walked around a bit and got it back past 90/50.