hallgod33
hallgod33 t1_j8wtwpw wrote
Reply to comment by FUNNY_NAME_ALL_CAPS in Psychedelics activate the same receptors as serotonin, so why aren't we always tripping? Psychedelics may cause neuronal plasticity and relieve depression by activating intracellular serotonin receptors that serotonin itself cannot, suggests a new study. by rjmsci
Trip-free derivatives already exist, like bromo-LSD is used for cluster migraines. Shulgin invented a boatload of non-psychedelic analogues to the classical psychedelics.
hallgod33 t1_j8i5t0t wrote
Reply to comment by I-Way_Vagabond in A study in the US has found, compared to unvaccinated people, protection from the risk of dying from COVID during the six-month omicron wave for folks who had two doses of an mRNA vaccine was 42% for 40- to 59-year-olds; 27% for 60- to 79-year-olds; and 46% for people 80 and older. by Wagamaga
I've got a BSPH, and I'd say that is a huge barrier no one wants to tackle. Medical anthropology is designed to help reduce the communication barrier, but no one in practical medicine wants to listen. Even though we use the same English words, the grammar and sentence structure and etc make medical science a functionally different language.
hallgod33 t1_j8x3mjs wrote
Reply to comment by FUNNY_NAME_ALL_CAPS in Psychedelics activate the same receptors as serotonin, so why aren't we always tripping? Psychedelics may cause neuronal plasticity and relieve depression by activating intracellular serotonin receptors that serotonin itself cannot, suggests a new study. by rjmsci
True that, a lot of Shulgin's work will never be peer reviewed so its hard to elucidate which compounds are providing the effects through human models. And the human models are self-reported and all that. But there are non-psychoactive preparations of a bunch of classical psychedelics that provide anti-depressant effects. What makes it non-psychoactive and effective is hard to pinpoint but Shulgin had a lot of raw data available for anyone interested to explore.