mcgato

mcgato t1_j9kaen9 wrote

Reply to Artists that play their full album on live shows by hjvkjvkjvg

Around 2008, I saw Sonic Youth play all of "Daydream Nation" at the McCarron Park pool in Brooklyn. I think that it was the anniversary of its initial release. Good fun, and The Slits opened up. I had never seen The Slits before, so a good night overall.

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mcgato t1_j2uoq8o wrote

Reply to comment by Direct_Age_2279 in TIL A former Catholic priest once ran onto the track during a F1 Grand Prix and also ran onto the track during the Olympics and cost the runner a gold medal by mintwolves

The name of the marathoner is usually listed as Vanderlai de Lima. I guess Cordeiro is his maternal family name. I watched the race on TV, and I believe that he would not have won the Olympic race, irregardless of the nut case that tried to tackle him. Most other knowledgeable followers of the sport also tend to believe that. He had been fading at the time of the attack, and the two following him were closing quite a bit in the final stages of the race.

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mcgato t1_j2kzuqp wrote

Reply to comment by scottyboy218 in When pharmaceutical companies develop new prescription drugs, do they test every method of delivery to the human body? For example, injected, orally, topically, rectally, etc? by scottyboy218

In that case, I think that pharmokinetic and pharmodynamic information is used to determine how the drug interacts with the body. As I understand, the pharmokinetics looks at how the drug gets into and around the body, which involves dissolution of pills in the digestive system or movement within the body after injection. The pharmodynamics looks at how the drug interacts in the body with the target of the drug, such as binding to receptors of interest that affect the disease of interest. So the mode of drug delivery that is developed is determined to maximize the effective drug delivery to where it is needed in the body.

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mcgato t1_j2kv4it wrote

Reply to When pharmaceutical companies develop new prescription drugs, do they test every method of delivery to the human body? For example, injected, orally, topically, rectally, etc? by scottyboy218

Your question seems to assume that the drug is submitted to regulatory authorities for approval with no thought to how the patient will take the drug. A drug is submitted for approval for a specific mode of delivery to the patient. If the drug is developed for oral delivery using a pill, the submission is for oral delivery using a pill.

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mcgato t1_iyf9l40 wrote

Reply to comment by teethalarm in ELI5 why fraudsters like Anna Sorokin managed to deposit bad checks and immediately withdraw cash elsewhere without banks stopping it? by 6horrigoth

I was on grand jury duty and had a case like this presented. A smallish business used a courier to take checks to accounts. The courier used the account and routing info from those checks to get checks for himself. He would then pay his bills with those checks, except he would overpay. So bill for $120 would get a check for $1120. He would contact the company about the overpayment, and get a refund check from the company. We voted to indict.

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