sciolycaptain
sciolycaptain t1_j9uoxo9 wrote
Reply to comment by Whiterabbit-- in Does the common flu vaccine offer any buffer against H5N1 (Bird Flu)? by Esc_ape_artist
The current influenza vaccines are made by incubating the virus in fertilized chicken eggs. That step takes time. and hundreds of millions of eggs.
With mRNA vaccines, you can just throw templates, nucleotides, and enzymes into a container and get more mRNA for the vaccine (extremely oversimplified)
sciolycaptain t1_j9u8fp0 wrote
Reply to comment by DiceMaster in Does the common flu vaccine offer any buffer against H5N1 (Bird Flu)? by Esc_ape_artist
Influenza vaccines can't be frozen without having decreased efficacy. They have a narrow window of temps they can be stored in a refrigerator, and once room temperature, must be used within 72 hours.
sciolycaptain t1_j9u48fn wrote
Reply to comment by Ch3mee in Does the common flu vaccine offer any buffer against H5N1 (Bird Flu)? by Esc_ape_artist
Making influenza vaccines is something the world has experience and capacity to do (because we do it every year), however current techniques still have a bit of lag between identifying a novel strain and then development and mass manufacturing.
If we looking at the 2009 H1N1 outbreak, it took about 6 months to have a specific H1N1 vaccine approved and distributed after the first human cases.
With mRNA vaccines, which they are looking into for influenza, the turn around time may be significantly shorter.
sciolycaptain t1_j7xp26m wrote
Reply to comment by pspahn in According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico
Please read beyond the headline. This paper was studying clot prevention in a very specific patient population, those who had bone fractures in the lower extremity. It excluded pregnant patients, because almost all studies exclude pregnant patients.
Your wife taking LMWH is probably for a very different reason. Aspirin should be avoided in later pregnancy unless advised by your physician.
sciolycaptain t1_j7whrwo wrote
Reply to comment by Yoshi_87 in According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico
You've had continuous lower extremity fractures for 25 years?
sciolycaptain t1_j7wh7qj wrote
Reply to comment by Hapgam in According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico
This study is in line with previous studies comparing aspirin to LMWH in this specific population of orthopedic trauma.
This was a larger number enrolled and showed low dose aspirin is non-inferior to LMWH for all cause mortality. But LMWH had lower instances of DVT and PE.
sciolycaptain t1_jcrogji wrote
Reply to comment by Long-Piccolo-3785 in Two rescued after accidentally being dumped in garbage truck by Sandstorm400
It's very nearly r/OrphanCrushingMachine