I'm curious if it has to do with the major blow Alzheimers research took when it was discovered that a big chunk of our understanding was based on fabricated data.

https://www.sciencefriday.com/segments/alzheimers-research-fraudulent-data/

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Probably it is. We're basically back a couple steps in our understanding. Though with the ultra rich growing older, we'll probably see research funded by them to make it faster

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Pretty sure the ultra rich have always been getting older and replaced by younger generation? What would be changing now?

They’re hoping the state of modern science combined with their immense west will give them extended or even eternal life.

I've been reading a lot about metabolism since my mother's death to type 2 diabetes. In those discussions, Alzheimer's disease is infrequently described as type 3 diabetes. I think maybe the cure for type 2 diabetes and many cases of Alzheimer's is so unpalatable that they've decided not to discuss it.

If we all suddenly stopped buying food-like products much of our economy would collapse.

the boomer generation is unaturally wealthy. millenials are poorer than our parents solely because of how much wealth the older generations are currently hoarding. on top of the elderly making one of our biggest segments of our population since a ton of children were born after WW2. also on top of science advancing at one of fastest rates in human history making it possible to start funding these crazy research projects or methods of increasing longevity.

We discovered a kind of plaque that builds up during alzheimer's so for a while there was a very plausible "so if we clear that out, we cured the disease, right?" that made it seem like the cure was in sight. But then we found drugs that cleared it and it didn't really improve anything. The drug still came out, there was a bunch of fraud where it tried to claim smaller and smaller effects, then just came out as being a totally do nothing drug. So now the research is back to "we have no idea how to treat this"

I've heard similar lately, that it could be a side effect of the body failing to process glucose as we age, leading to mitochondria damage in brain cells, so in effect it' could be related to diabetes. I don't have details, just seen it mentioned twice now over the past few months from different sources.

It certainly could, yes. At this point we're back at ground zero in Alzheimer's research. Perhaps once the scientists look at the data without the bogus research the real cause will pop right out and we'll have a potential treatment path in a few years or it could take another 30 years to get where we need to go. There's no way to tell at this point.

It's quite frustrating that all that time and money have gone to waste. :-(

eh you never know, understanding how the plaque works and how to get rid of it may yield something beneficial in the future.

Exactly. In addition, the effort is never wasted. If we wouldn’t have looked into that direction, we never would have determined whether it was a viable solution or not. It’s all part of the process of research.

It wasn't anywhere as big a blow as people made it out to be, the truth is that researchers had been suspicious for a very long time and many other avenues were being investigated simultaneously,

Did anyone try to simply stop with sugar and all the refined crap?

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High dose of CBD oil clears the receptors that cause alzheimers

Reminds of the Edison legend where he "found 1000 ways to not make a light bulb."

Nope. Nobody's ever tried that before.

Association Between Consumption of Ultraprocessed Foods and Cognitive Decline

Yeah, seems plausible enough

Maybe they should

It could do wonders to your body granted you go thru withdrawal for about a week

That’s actually a good place. Blank slate, know what doesn’t work.