screen317

screen317 t1_jbsngi7 wrote

> OP, the virus mentioned doesn't really represent an organism because it requires the mechanisms of a cell to replicate

There are a slew of obligate parasitic eukarotes that this definition disqualifies as an organism.

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screen317 t1_ir8ri2z wrote

> Abnormal T-cell malignancies, therefore, most commonly present as a hematologic malignancy which is to say the problem is in one of the early stage cells in the bone marrow

This is not accurate. ETPs (T cell precursors) don't have their Rag genes active and wont be susceptible to T-ALL. So, there aren't really any BM-derived T cell malignancies. It's primarily Pre-T ALL that originates in the thymus, since those are the cells actively rearranging DNA.

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