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[deleted] t1_ivgr82k wrote
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Outrageous_Cry_5945 t1_ivgrii1 wrote
The main mechanism is less exposure to estrogen. The title is a bit misleading & makes it sound like the writer(s)/scientist(s) have an agenda to spur population growth, but one can achieve similar results without being pregnant (reducing levels of estrogen through other means, e.g., small molecule therapeutics, aromatase inhibitors like letrozole, anastrazole, et cetera).
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thetransportedman t1_ivh2qrv wrote
This isn’t new. Each baby is a 9-mo pause on menstruation which is the growth and death of endometrial cells which is carcinogenic in nature
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Mercuryblade18 t1_ivh4rgr wrote
This has been known for awhile. Also, if you don't want to have kids and want to decrease your chances of endometrial cancer and progesterone secreting IUD is a great option.
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footcandlez t1_ivh5gkv wrote
What's new is right there in the article:
“While previous studies have shown multiple pregnancies and using the oral contraceptive pill can reduce the risk of endometrial cancer, this is the first study that used genetics to study multiple risk factors at once.”
Set-Secret t1_ivh7rhh wrote
This was already well established. Its literally in medical textbooks.
Nixplosion t1_ivh7v9w wrote
That method of prevention is just as expensive as medicine.
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Fit-Rest-973 t1_ivh8rwn wrote
More than two full term pregnancies affect a woman's health adversely
glefe t1_ivh9fda wrote
Are there side effects to progesterone secreting IUDs?
Ok_Skill_1195 t1_ivh9qgo wrote
Yup I'll stick to my IUD. No periods, no babies. Best of both worlds.
Ineedavodka2019 t1_ivha041 wrote
How. Any links? I have never heard this.
texasspacejoey t1_ivha2x7 wrote
Ya but it's probably cheaper to cure the cancer
[deleted] t1_ivhbwa8 wrote
Only if you keep them all!
juspooped t1_ivhcd1l wrote
More specifically, estrogen causes endometrial hyperplasia which is increased number of cells growing. More estrogen exposure = more endometrial cell growth. In pregnancy, there’s a 9 month pause on that cyclic rise and fall of estrogen.
Fit-Rest-973 t1_ivhcv7p wrote
OB/GYN had told me, when we worked together. Makes sense. Stretching the body would predispose one to bladder and uterine prolapse, to begin with
Mercuryblade18 t1_ivhcyow wrote
1:1000 risk of uterine perforation, which isn't as exciting as it sounds.
If you get pregnant with an IUD you do have a higher rate of an ectopic pregnancy than other forms of contraception but your rate of ectopic is still lower than the general population.
You don't have the "first pass effect" you get with combined oral contraceptives. It has less side effects that other systemic exposure birth control.
Every obgyn I know has an IUD as their form of contraception.
EDIT: Unfortunately every single medication and treatment has side effects, you should discuss them with your doctor. If I didn't prescribe things because someone somewhere had a bad time with it... I would never prescribe anything or ever operate on anyone.
floatyfungling t1_ivhd5hl wrote
I bet a hysterectomy does a much better job tho
DavinaCole t1_ivhf1s2 wrote
So stoping periods via birth control would in fact do the same thing?
Potanko_Prime t1_ivhf811 wrote
Got one when I first started transitioning cause of doesn't affect testosterone like other birth control options, and it's fantastic
pink_turtle_23 t1_ivhfzaa wrote
Thats because people specifically don't tell women how damaging pregnancy is to a woman body in case they decide not to have children.
Hydrate-N-Moisturize t1_ivhh0rh wrote
Thats cool, but the cost of babies makes you wish you'd just take the cancer.
Fit-Rest-973 t1_ivhh31z wrote
Which is common sense. How many times can you overstretch a rubber band before it breaks?
RearEchelon t1_ivhh5iz wrote
Still not worth it
fighterpilotace1 t1_ivhhruy wrote
No babies for the machine.
thetransportedman t1_ivhi4wv wrote
Correct, similar association have been shown
alsotheabyss t1_ivhikyc wrote
Having more babies or taking hormonal birth control that includes progesterone. This issue is exposure to oestrogen, and being pregnant and taking the Pill both reduce your exposure.
It’s very annoying that a lot of headlines and reporting on this has focused on the kid-having, not the reducing exposure to oestrogen.
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KeybladeMasterAqua t1_ivhjze3 wrote
And it also increases risk of heart disease, diabetes, tumors on the ovaries, stress related disease, poverty-related illness, and others. You know what also reduces endometrial cancer? A hysterectomy. Same with getting your fallopian tubes being removed reduces ovarian cancer risk.
If the idea of having a lot of babies is only appealing due to not wanting cancer, get your reproductive organs removed if you’re so concerned. It’s safer and easier that way.
[deleted] t1_ivhk8uy wrote
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KeybladeMasterAqua t1_ivhkcyy wrote
And then there is a chance of dying in childbirth. You can’t get cancer if you died bleeding out during labor, right?
chainedflower t1_ivhkg0l wrote
they are basically explaining that if you have more kids the odds are smaller for you. just like gambling.
sigzag1994 t1_ivhkh0i wrote
I’ve had one for 3 years and unfortunately for me it has destroyed my sex life. Sex is now very uncomfortable and I have low libido, still (I was told these issues would resolve over time). I have gotten checked to make sure it is positioned correctly, and it is. I also have super painful (though light flow) periods that last like 10 days. Barely any blood but lots of cramping.
Most people seem to like IUDs so maybe I’m just unlucky.
[deleted] t1_ivhl0mm wrote
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QueerAsInFUN t1_ivhl24x wrote
If you can get one, depending on where you live.
derycksan71 t1_ivhlyc1 wrote
Which introduced it's own set of risks and side effects. It's not something to be performed lightly.
Tony2Punch t1_ivhlz4f wrote
This study was targeted at genetically studying multiple risk factors.
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Scarlet109 t1_ivhoild wrote
Still not going to be having any babies
agentfortyfour t1_ivholx3 wrote
My daughter has endometriosis and is quite knowledgeable. It’s entirely possible for endometriosis to re grow even after a hysterectomy. It’s not always an effective strategy. Finding an nook surgeon to excise the offending tissue is still the best treatment.
ardvark_11 t1_ivhoz6a wrote
Had a horrible time with mine as well
cheshire_kat7 t1_ivhp0o7 wrote
I tried a progesterone only pill for while. I ended up having bleeds every other week - it was like my menstrual cycle was just 2 weeks long.
I went back on the regular pill and it took a year before my uterus fully settled down. Technically, being on the pill is risky for me (age, weight and a family history of DVTs) but this point I'm afraid to try anything new in case it plays havoc with my cycle again.
thetransportedman t1_ivhpnny wrote
The genes mentioned are ones associated with increased child births a la fertility genes
_tiny-but-mighty_ t1_ivhpq1v wrote
Meh, I’ll take my chances
Edit: I can’t believe this comment got me reported as suicidal.
Alternative-Flan2869 t1_ivhqnjc wrote
…and instead gives you____.
[deleted] t1_ivhv468 wrote
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Mercuryblade18 t1_ivhwefr wrote
Yep, no drop on libido either from it.
Mercuryblade18 t1_ivhwtsu wrote
It can affect acne for some, but it did not cause weight gain. Every medication has potential side effects unfortunately. IUDs seem to have the lowest.
There's no such thing as a "better form" of progesterone, that's just marketing. Slynd contains the same progesterone as Yaz. Mileage will very, that's why it's important to experiment with what form works with you best.
Mercuryblade18 t1_ivhx620 wrote
Sounds like aommething else is going on that may not be the IUD, I'd ask your doctor about pelvic floor physical therapy or evaluations for other causes of low libido and pelvic pain. You can also have it removed and try a different form of contraception to see if you have better results.
Very little hormone becomes systemic with the IUD hence why it has better side effects profiles that pills, rings, shots or the arm implant.
TheSinningRobot t1_ivi0iod wrote
Just to clarify, is progesterone itself effective as a birth control? Or would you have to use it in conjunction with other contraceptives?
Brainiac_Side-Goof t1_ivi0m7c wrote
No… that is not how you start a conversation and it sounds like you’re smoking your own fumes. It’s my death but I dig this grave and present it to the crowd. Look at the fax, this is where I go to die and that is where science goes to die. Do I see a difference? No! Did you ask? No, so then send me off to God and all is good. All in a day’s work. This post will be removed. Question what is an anecdote? Is free speech even partially allowed? Is this subreddit rigged? One thing I do know is that mods can often be the most hated form of existence according to memes if this has any relevance. I’m trying not to break rules that already seem broken in the first place.
glycophosphate t1_ivi2nbk wrote
I had my uterus removed. That got rid of the risk of both babies and endometrial cancer at the same time!
gambitz t1_ivi2rye wrote
I had an IUD for 10 years and no period during that time, wouldn’t that effectively do the same but better since I was no longer menstruating?
Mercuryblade18 t1_ivi3ojq wrote
depending on the form and how you take, its a contraceptive
MunchieMom t1_ivi5rl2 wrote
Oh so I can just suppress my period with birth control and have it way easier?
Except for the part where I have endometriosis. That can't be good in light of this study.
DarkHater t1_ivi6m7n wrote
Badda bing, badda boom! Like petting two dogs with one hand.
OhtareEldarian t1_ivi7tdh wrote
Neither is being a baby factory.
thereisafrx t1_ivic2ff wrote
Soon, procedures like this likely will be illegal to do electively, because the republican government wants to tell women what to do with their bodies (unless it's get a life-saving vaccine for the public good...).
It's the next logical step after they outlaw birth control pills (which is already being worked on).
glycophosphate t1_ivica59 wrote
Oh I had a sizeable fibroid tumor to use as an excuse.
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sigzag1994 t1_ividilo wrote
Was never an issue before the IUD
geekgurl81 t1_ivifoib wrote
Interesting it doesn’t mention breastfeeding at all, which also suppresses estrogen, at least somewhat. I wonder if lactating makes any difference.
Mercuryblade18 t1_ivilqgn wrote
Why do you still have your IUD? Remove it and see if your symptoms improve.
[deleted] t1_ivioopm wrote
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LowlyScrub t1_iviozcy wrote
You could have pissed some muscles off during the insertion. Have something shoved through your cervix is quite jarring. I was cramping terribly for 2 days.
sigzag1994 t1_ivir96r wrote
Fair question. The insertion process was so horrifically painful that I was afraid of the removal process. Also I never had a good track record with BC pills, so once I had the IUD in I tried to stick it out
sigzag1994 t1_ivircpa wrote
2 days sure, but multiple years?
YommiaDidIt t1_iviri6u wrote
Thats why female dogs are sterilised.
LowlyScrub t1_ivirzva wrote
I don't know, muscles are wild down there. Not saying your suspicions aren't reasonable, just that you shouldn't discount your pelvic floor causing issues. I feel like I am constantly fighting the keep my hips, lower back, and lower abs loose.
erehin t1_iviwq3d wrote
Yeah this article title gives me strong pro-lifers-are-going-to-start-pretending-endonetriel-cancer-is-the-leading-cause-of-womens-health-issues-and-death vibes
Melti718 t1_iviwuj4 wrote
Im sorry, this reads like your having an episode. I hope youre better soon
KeybladeMasterAqua t1_iviwzxz wrote
Yeah. That’s what I fear. It will give conservatives more ammo to take away contraceptives. I, myself, would die before the second trimester because of preexisting conditions. But apparently I “don’t exist” in the eyes of pro-lifers. So I must die if I get pregnant. Not allowed to have an abortion if something happens.
erehin t1_iviyelu wrote
My best friend too. Solidarity sister
LemonTheTurtle t1_iviyts0 wrote
It's more than 9mo actually. Women don't have menstruation few months after giving birth. It differs from woman to woman but it's definitely longer than 9mo. That's why many people think they can't get pregnant in the few months after giving birth but that's obviously wrong
Brainiac_Side-Goof t1_ivj1l42 wrote
No, I hope you are doing better soon. You see, my suffering is my gain. I always suffer so I always have room to learn how to win in life. Think for once! PETER PARKER JUST GET IT INTO YOUR HEAD …Candice… you see I have the memes. You can’t win against these memes.
AdPretend1573 t1_ivj37ax wrote
Funny how they didn't mentioned endometriosis can cause infertility as well.
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Zeno_the_Friend t1_ivj6d1e wrote
So does a hysterectomy.
Works both ways. Use it or lose it.
Strazdas1 t1_ivj7c21 wrote
Thats only small part of the world, though. And can be changed through voting.
Ricksterdinium t1_ivj9bsk wrote
So ladies come and get your medicine. It's free on the house.
derycksan71 t1_ivj9jil wrote
Nobody is forcing childbearing. However, I do highly encourage you do some research on hysterectomy before being nonchalant about the procedure. Early menopause and cardiovascular disease risks alone should be enough to realize, hysterectomies are a last resort option, not a default or preventative care.
MelanieSeraphim t1_ivjamg9 wrote
Too bad you can't have a hysterectomy when you're done having kids. My insurance denied it after I became severely anemic from blood loss secondary to fibroids and polyps everywhere. They keep performing painful D and C's, but they just come back.
I hate my diseased uterus. Looking into traveling to Canada to have it yanked out.
crazyhadron t1_ivjbfq8 wrote
Men get a similar benefit from either being sexually active, or just snipping off their balls.
It has been observed throughout history that eunuchs, while they tend to become fat, live longer than their whole counterparts.
I'd rather jerk off everyday, though.
AceTygraQueen t1_ivjcrb6 wrote
Who funded this research? The Duggars?
stepfordexwife t1_ivjexwe wrote
Ehhh that’s not true. I definitely had a drop in libido but it was still worth it for the ease of use. Everyone’s miles will vary but side effects are usually mild if people experience them and go away over time.
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queefybean t1_ivjha3u wrote
I’ll risk the cancer ta
Spiffy_Pumpkin t1_ivjhajn wrote
I'd imagine getting it removed via hysterectomy or endometrial ablation is just as if not more effective then, right?
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Mercuryblade18 t1_ivjjy7e wrote
Yes I'm aware Slynd doesn't have estrogen. But everyone's body will respond to different forms of contraception. You shouldn't make your birth control choices based on other's anecdotes. You should talk to your doctor about potential side effects and what the quantitative risks actually are and see what's right for you.
Edit: I should add- Drospirenone is also likely the most thrombotic of the progesterones, probably a lower risk than estrogen containing pills but I wouldn't recommend using it if VTE is a huge concern- It's likely safer to take a different form. However, if it it's the one you tolerate the best it may be reasonable to assume the small but higher risk of a VTE, the data is still murky.
Confident_Bridge9811 t1_ivjkscd wrote
>Nobody is forcing childbearing.
Uhhh.... in the US we certainly are trying.
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derycksan71 t1_ivk62ry wrote
Ok....conception isn't forced (excluding rape wich is illegal)
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theoneandonly6558 t1_ivkncp3 wrote
Yes, but...
The "mini-pill" or progesterone-only daily birth control pill is slightly less effective than the traditional combination pill. The main issue is taking it at the same time every day, and if you miss that 3 hour window you have to use backup birth control. The traditional pill is less picky about when you take it/missed pills.
TheSinningRobot t1_ivksj18 wrote
But the iud solves this issue no?
DarthRevan1138 t1_ivkt6q7 wrote
Rather die of cancer if I were a woman if I'm being honest.
Plane_Chance863 t1_ivktk4j wrote
Actually I've read about women complaining that their doctors refused such procedures because hey they might want to have kids one day!
GenuisInDisguise t1_ivky8ll wrote
It works for dogs why not for humans?
Had two dogs pass away from endometrial cancer because they never gave birth and is a common thing among large breed dogs
RevolutionaryDrive5 t1_ivl0519 wrote
tbf living past 25 can also cause damages to woman body, respectfully
theoneandonly6558 t1_ivl4cdp wrote
That is correct.
Mercuryblade18 t1_ivms72q wrote
A hysterectomy can (and often is) performed without an oophorectomy (removing the ovaries) and therefore cardiac affects and menopause aren'ta factor.
derycksan71 t1_ivmwx9r wrote
Sure but we're talking about endometrial cancer prevention/treatment which the most effective treatment is a full hysterectomy. Even if an partial hysterectomy is performed it still does not prevent ovarian cancer which, while less common, is far more deadly.
The whole point of this study is the hormones introduced from pregnancy, particularly progesterone, are what have the benefit for cancer production. Hysterectomies are not typically performed for preventative care.
Mercuryblade18 t1_ivmyfw6 wrote
To prevent cancer? In a patient with abnormal endometrial tissue - a hysterectomy without oophorectomy is reasonable, oophorectomy is only recommended if you have actual cancer or atypical hyperplasia on biopsy (since the risk of an occult malignancy is high).
No need to take out the ovaries on a 40 year old with abnormal bleeding and risk factors but no actual cancer. Endometrial cancer is slow growing and acts locally until its advanced stages.
derycksan71 t1_ivn4l4e wrote
Prophylactic hysterectomy are typically only performed on women with high risk gene mutations. Three of the top mutations for endometrial cancer are also indicators for ovarian cancer, because of this, removal of ovaries and tubes are recommended when those genes are present.
We're getting into pretty individualized situations, not general prevention as this article is discussing.
Mercuryblade18 t1_ivn6xl5 wrote
Yes, in a genetic cancer like Lynch you would take out ovaries.
In a patient with an abnormal biopsy that doesn't want to take progesterone to see if it regresses a hysterectomy is a form of prophylaxis
Endometrial hyperplasia with or without atypia is fairly common especially in obese women.
As far as general prevention? No, we don't just cut out uteruses, and now we're in the weeds, but you didn't talk about hysterectomy with or without oophorectomy because I think it's clear you didn't know the actual difference or you would've specified in your original comment. It's okay to admit you were wrong rather than trying to Google answers that make you technically correct. What's your background in this?
If a patient asked one of the gynecologists at my hospital for a prophylactic hysterectomy 1) they wouldn't likely do it but also wouldn't take out the ovaries unless that had some other risk factors.
Most hysterectomies under the age of 50 are performed without an oophorectomy.
We don't use terms like "partial" or "complete" anymore, those are outdated and not uniform.
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