Submitted by TheRappingSquid t3_122bq27 in Futurology

So organ printing is getting pretty far. Reckon we'll see a time where we'll straight up get organs made of plastic that surpass the one's we're born with? Maybe even soon? Plastic 'n tech can break, sure, but it can't get sick. Will old folks with printed hearts not have to worry about heart disease? How might this effect aging?

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BeeEven238 t1_jdppso1 wrote

Bro, I can’t even go 2 years without having to replace my headlights in my Tacoma…

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HackDice t1_jdqa49m wrote

if replacing headlights meant having to open up someones chest and rip open their rib cage, they'd probably make them a bit more durable.

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fitm3 t1_jdqfqq2 wrote

Naw they’d bake in an easy access port to the body and implement planned obsolescence to ensure regular expensive surgical maintenance and care to milk insurance.

Edit spelling easy

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Lunchboxninja1 t1_jdqgnsl wrote

Fuck youre right. I hate capitalism

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psychotobe t1_jdqjy23 wrote

There's a point where a product becomes too inconvenient to buy, and it stops selling. People don't buy with no mind. That's what doomers who believe in that npc nonsense think. People are lazy about research not actively suicidal in their apathy.

If you sell an organ that fails every time and needs to be replaced. That organ will not be bought. It's to expensive to keep getting it and someone will sell a cheaper one to undercut competition. Apple gets away with it cause their a status symbol. No one can show off their custom heart to wow the common folk. It works less well if it's not packed in properly

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edutained t1_jds3ua0 wrote

They can if a patent is held and they kill all the competition in development or court. It's already being done with tons of pharma.

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dickinsauce t1_jdu39ja wrote

Ugh capitalism. I’m going to HATE when they charge money to save my life and drastically improve my everyday life. This system is the worst

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Gubekochi t1_jduc9bw wrote

Healthcare is a right, not a product. As such it is free at the point of service in most of the civilised world.

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dickinsauce t1_jdywirv wrote

No it’s literally not. You can believe and hope it is all you want, but unfortunately it is not. And just because it is paid for by governments in other countries does not mean that it is a “right” there either.

The American system is hugely broken and needs an overhaul. But to believe because you are born you are entitled to other humans caring for/mending you is asinine.

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Gubekochi t1_jdzrbiq wrote

First: all rights are made up. Second some country have it in there constitution that healthcare is one of the right enjoyed by their citizens. So that's that. You being ignorant about them doesn't change the facts and reality of how people live. You may not like it but this is what peak human rights look like.

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dickinsauce t1_je31w2j wrote

Lmao, did you intentionally use the the meme format of “you may not like it but this is what peak ____ looks like?” Cause If yes, very funny. If not, then you may have the brain worms.

Please find me a constitution with healthcare as a “right”. I just looked and couldn’t find one. I’m sure you will provide me a list of countries that provide free healthcare, which again does not mean it’s a right.

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Gubekochi t1_je3gbaz wrote

I don't see how your ignorance/google ineptitude really has anything to do with me... and why I should be given homework to compensate for your apparent lazyness... so I'll give you the first result on my google research:

>Article 36 (3) of our Constitution emphasizes the obligation to protect the national health of the nation by stipulating that “all citizens are protected by the state in relation to health.” This means that the right to health as a social fundamental right is the most important aspect of health rights.

That would be S. Korea.

Also, (bonus down the google research) the EU Charter of Fundamental rights has it so Citizens of any European country that recognize that Charter as valid would have a right to health care even if their country doesn't specify it in it's own constitution. So there's that too.

Lastly, it was an intentional use of the meme, but IF I had brain worms, I could get my head checked for free since I don't live in a third world country.

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dickinsauce t1_je8hulc wrote

A+ on your homework and your sense of humor than. On time too!

Good to know thanks. You’re right then.

My point, which I think intersects with your other comment is that a right is something inherent. In my opinion a right is something you “have” from the moment you’re birthed. The list of those rights is extremely small.

Governments can give you other rights like we have in the US. My bet was that while they’ve nationalized healthcare in many countries, they wouldn’t list it as a right. Because in my mind, that means no refusal of service no matter the procedure/ailment. As mentioned I was wrong.

But I stick to my point that healthcare is a product and the only nuance is who is paying.

Boiling it down if we go into the apocalypse tonight and a baby is born in the woods of South Korea tomorrow, no one is going to stop everything theyre doing for themselves to survive in order to go to tend to the baby. But the babies right to pursue happiness, live freely, and speak whatever it wants to speak (once able) still will be there.

That’s how I view a right

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Gubekochi t1_jecbelj wrote

>But I stick to my point that healthcare is a product and the only nuance is who is paying.

We also have a right to a certain amount of security. That's why countries have armies and police forces. Those (ideally/theoretically) exist for defence and to maintain orders so citizens can pursue happiness and not get raided by hordes of barbarians or assaulted or what have you. That's what government are supposed to exist for. As a society we decide that something is important for everyone, we put our money in a big pool and we use the pool to ensure that the underlying right is secured.

It works for the army and the police in the US, it also works for healthcare elsewhere.

Of course it's not free and someone pays for it. Same as roads and fire stations. You don't pay when you need them, they're paid for from taxes because they help society function (and healthy citizenry can be argued to also do that).

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dickinsauce t1_je320ip wrote

Also, “rights are made up”. K so saying healthcare is a right is a made up meaningless statement? Just confusing

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Gubekochi t1_je3f1dc wrote

Justice is made up. Good and evil is made up. Those are all concepts that mean different things to different people from different time and culture. It means what it means.

When I say something is a right, it is meant as "in a proper society, it should be treated with the same importance we give to other rights".

Nothing has inherent meaning. Meaning is something we construct to not go insane from a meaningless universe because our brain has evolved to recognize patterns as a way to improve our chances of survival and has gotten too good at it for our own comfort.

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WimbleWimble t1_jdqii0h wrote

iKidney ...takes until version 6.5 before it produces urine, but other offbrand kidneys have had the feature since day 1.

Apple claims it invented round blood cells.

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Top_Requirement_1341 t1_jdqm1io wrote

Your iKidney 6.5 has reached end of life.

If you still need this function you will need to upgrade to iBody 2, with embedded iPhone.

Upgrades to iBody 2...

By clicking this you accept tracking of your location, and that all live streams of all of your senses / sensors will be shared with our advertising partners.

Clicks cancel.

By clicking this you accept tracking of your location, and that all live streams of all of your senses / sensors will be shared with our advertising partners.

(Meanwhile, the beeping from iKidney 22 turns from "panicked" to "frenzied".)

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WimbleWimble t1_jdqsrar wrote

we've slowed down your iKidney to preserve its life.

it will now take 2hrs to empty your bladder.

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HackDice t1_jdql9ml wrote

why bother with PO, when they can just charge you a monthly subscription instead. PO is becoming out-dated in leiu of just, hardware that requires software to run. Your organs will be on monthly subscription. Don't meet your payments? We'll find a way to make you make your payments. Otherwise, well, nobody ever seems to care when landlords evict families onto the street, why would they care when we evict your organs from your body?

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Carbon140 t1_jdqfyaj wrote

Nah, the movie repo men seems like a more accurate depiction of how synthetic organs would play out.

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LewLew2019 t1_jdqfja2 wrote

Yeah, those arnt built to last, they're built with a shelf life so you buy another set

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Robotman1001 t1_jdri6je wrote

To be fair, most headlights functionally last 15 years. I would happily take a new organ ever decade and a half if it meant improved functionality.

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FeatheryBallOfFluff t1_jdpw597 wrote

I think you have a better chance with printed living organs from the patients own stem cells.

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WimbleWimble t1_jdqim8w wrote

Oh god, I'm dying..print me a new heart!

Unable to print HEART. Out of Liver Cells. Please replace Cartridge.

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Gubekochi t1_jducimr wrote

All the convenience of printers and the pleasure of heart surgery? Is this heaven?

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TheRappingSquid OP t1_jdpwn80 wrote

Fair enough, but I was thinking about how cell's degrade with age, y'know? If there was a way to print "fresh" organs without the sort of genetic damage, then that'd be great too.

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FeatheryBallOfFluff t1_jdq01au wrote

Yes, if genetic damage can be reversed and then those cells are used to print organs, you'd be "born" again. The advantage of that is that those organs can regenerate, whereas plastics may degenerate. But if there are applications where plastic is more durable, we should use those.

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IndigoFenix t1_jdrn4vb wrote

Just need to figure out how to turn on and off cancer mode in cells.

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BasvanS t1_jdq72hp wrote

Cells don’t degrade as much as they lose their ability to regenerate. Cells rejuvenating is all but what you want from printing fresh organs. Adding plastic to the mix, in my opinion, causes more problems than it solves.

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OffEvent28 t1_jdsqxri wrote

The whole printing organs business will be based on using the patients own stem cells to create the new organ. Rejection problems will not exist with this technology.

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Gubekochi t1_jducky7 wrote

Look up Yamanaka factors. Cells can be deaged.

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TheRappingSquid OP t1_jdys2n2 wrote

I did, they are interesting :o I hope that goes somewhere, if not just to quell my fear of mortality '>->

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Gubekochi t1_jdzs2lz wrote

It is currently being studied by Dr. David Sinclair and showing great promises.

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TheRappingSquid OP t1_je2qe74 wrote

I've looked at that, and while I want to he optimistic, some of the information given there seems to be a bit vague. Like, all cards on the table, the mouse rejuvenation shit is IMPRESSIVE. But it doesn't seem like there's a whole lot of actual info being given about it, rather instead it seems there's information being given on the benefits of it. Also, how far along is that really? Because I've seen many of the same information recycled in different articles over the span of a few years-. I'll gladly believe it if I see anything else about it, but when it comes to fields such as gene therapy/rejuvenation for an extended health span, or space travel, or bionic arms, I feel like it's easy to get swept up in the hype of it rather than actually understanding it. Personally, I'm the type to fully believe that all that fun scifi shit can be real- maybe even soon, but I wanna make sure I have my facts straight too.

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Gubekochi t1_je2s805 wrote

Hope for the best and prepare for the worst.

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CatandmeVsSociety t1_jdr4czz wrote

Well and even a matching organ from the same blood type has a very good chance of being viewed as a foreign object in the body. I know there's different meds and procedures to keep that from happening but still, I think you'd have to trick the body into not viewing it as a foreign object..

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LS5645 t1_jdycsye wrote

The body pretty much always views it as a foreign object unfortunately, which means the current organ transplants (such as kidneys) will only last about 10 years or so before they get worn down by the body constantly attacking them (this is even with immunosuppressants), then the patient is back to their old state or possibly even worse.

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MadDocsDuck t1_jdq1hmk wrote

I'm not sure if I missed something but in my lecture on tissue engineering it sounded like printed organs are something like 20-30+ years away. There are problems with the cell density, the cell type diversity and the vascularization. We don't even have proper organ models for medical testing yet. And then you will have to go through all the clinical testing and legal processes. Don't mean to be a downer but I thing that is quite some time away, at least from what I've heard.

Also, I wouldn't expect them to surpass the real thing for quite some time after the introduction. They may be better than a failing organ but it is quite safe to assume that our organs are already performing at a very high efficiency rate given the biological compoments.

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Phoenix5869 t1_jdq3wob wrote

> 20-30+ years away

at best

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AndrewSshi t1_jdqlvg9 wrote

Like commercial fusion, twenty years away and always will be.

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Strungbound t1_jdqxeq6 wrote

There are good reasons beyond this besides "scientists overpredict all the time."

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RamaSchneider t1_jdq29kc wrote

(Asking from general ignorance) I've read about telomeres and telomerase and how the telomeres keep shrinking as our cells divide and how once that telomerase is gone, the cell is dead.

Any accuracy there?

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gopher65 t1_jdsjmbk wrote

That is just the cell's self destruct flag. It minimizes the chances that the cell will live long enough to aquire enough DNA damage that it becomes cancerous.

It's the "kill me before" date, if you will. That isn't what damages cells though. Living does that:P.

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IndigoFenix t1_jdrntah wrote

This is the primary mechanism, though the benefit for this system is that it makes cancer much less likely. A potential cancer cell must activate its telomerase production or the tumor will die once its cells have divided more than they are supposed to.

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RavenWolf1 t1_jdu2g2c wrote

The Current progress with AI probably will bring this tech way faster that 20-30 years. Especially if we get ASI at next decade.

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MadDocsDuck t1_jducokl wrote

Mate, AI will not solve all problems. You can expect it to take years until there is an AI capable of working on these problems. Biology/Medicine is a very AI unfriendly field because it is very expensive and time consuming to generate test data thus it is very difficult to train AI models.

Think about the GPT models, they have millions if not billions of examples. On the other hand, a simple cell line takes 6 weeks to grow, then sone time to perform experiments, then some for data analysis.

Even if there were 100k people (which is a generous estimate) working on this problem and we assume a generous 10 weeks per experiment and that all experiments are successfull there will be 520k experiments a year. That is such a massive overestimate and still not enough for a really powerful AI tool.

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RavenWolf1 t1_jdvy3eb wrote

ASI will solve all problems pretty fast if we get it. It is called technological singularity for a reason.

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D_Ethan_Bones t1_jdpo93s wrote

> Will old folks with printed hearts not have to worry about heart disease?

I'm not expecting the version-1.0 RoboHeart to be able to keep up with the American diet, it might be slightly better than the original thing but let's not have unlimited expectations here.

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Top_Requirement_1341 t1_jdqm7p1 wrote

Nah, you've got it all wrong.

The diet becomes mandatory to supply lubrication to the moving parts.

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UnionGuyCanada t1_jdqtur2 wrote

Even if the heart can pump through the tiny openings left by all the sludge buildup, the added pressure will blow out something else.

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BackOnFire8921 t1_jdq4vm5 wrote

I am ready to get ripped with some chrome, choomba!

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devi83 t1_jdq3fhq wrote

>Plastic 'n tech can break, sure, but it can't get sick.

There are organism evolving to eat plastic more and more. I suspect someday plastic diseases will come into play.

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TheRappingSquid OP t1_jdq6pk1 wrote

Oh my god imagine viruses made out of plastic. I dunno if it's possible, but them viral fuckers are WEIRD

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Ohigetjokes t1_jdqkc7b wrote

You have a point BUT there’s a progression here.

First they’re going to be crappy emergency-only replacements that break down. And it’ll probably be like that for 10-20 years.

Then they’ll move into the “pretty good option” phase when things go wrong but you can choose between a few treatments. That’s another 10-20.

Then they’ll be in the “unfair advantage” stage where they outperform natural organs and disqualify competitors. 50 years.

And then they’ll be the “most people get them in their late teens or twenties” thing, like braces.

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TheRappingSquid OP t1_je2tfeh wrote

Well I'm 20, so assuming I don't get hit by a bus or falling space debris or some shit I'll keep this in mind

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Mercurionio t1_jdpwv4p wrote

The question is in rejection.

Plastic won't be good anytime soon (I mean, without consuming drugs to contain them), while organic has issues of their own.

STEM is good and nice, but we won't know for sure, since it requires study in a long run ( I mean, we need to understand how it will mutate in human body, can we control it and so on in 20-40 years).

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Azarokkusu t1_jdq6ir1 wrote

People like Paolo Macchiarini really hurt plastics' and STEM cells chances too.

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ConfirmedCynic t1_jdpx6kd wrote

I don't know about organs made out of plastic, but it's conceivable that the cells employed for bio ones could be genetically modified to be improved over the originals.

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Zagdil t1_jdq3swz wrote

So far organs have proven to be too complicated to be easily printed let alone made artificially entirely. The only internal organ we even stand a chance at right now is the heart. The heart is surprisingly easy as it's just a sack of muscles, with blood vessels running around it. All the other organs are far too intricate and finely structured.

Looking into the future I would say, that organs grown from your own DNA in Zero G in orbit would be our best bet. A lot of things have to happen to make this affordable.

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gopher65 t1_jdsjz64 wrote

And the liver. A lot of the functions of the liver are done on a cell by cell basis. So a big glob of cells will do at least some of the work. But it isn't a full liver replacement.

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Phoenix5869 t1_jdq48y4 wrote

Printed organs / artificial organs are optimistically 20 / 30 years away at best. This frankly isn’t something you have to think about, at least not for a long time

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Initialised t1_jdqdzrq wrote

It’s probably going to be your tissue grown on a scaffold to avoid rejection rather than a full artificial organ as in Repomen but we might need those as regrown organs mature or as a stopgap while a spare organ is grown for you.

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WimbleWimble t1_jdqie62 wrote

2060 and the pacific organ patch is bigger than ever.

Scientists say for $40 billion, they've found a way to scoop up plastic kidneys, but hearts and minds are still proving to be a problem.

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ovirt001 t1_je0gmtp wrote

Too likely to be rejected and risks polluting the body. Not to mention any damage cannot be repaired. The replaceable nature of cells is an advantage for longevity if we can improve their function.

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TheRappingSquid OP t1_je2q1vw wrote

Fair enough point, but let me return with a counterpoint: what if instead of a big, clunky plastic organ, we used singular artificial cells instead? Like, say, individual, simple nano-cells programmed to replace dead organic cells? Think it'd be possible to create an artificial cell with such parameters as to deter rejection? (Maybe if you dressed them up nicely and gave them a bouquet of roses to give the organic cells?)

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ovirt001 t1_je5nl1v wrote

I think we'll eventually get there, no clue on a time range.

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BitchyWitchy68 t1_jdq3s62 wrote

The only people who would get them would be the super rich and I’ll be damned if I want those sorry bastards to live forever.!

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Imaginary_Passage431 t1_jdqdckg wrote

But after the rich got it, it wouldn’t be profitable to the owner of the immortality pill to wait for the 99% of humanity to get rich somehow. Thus, the price will be in the equilibrium of lowest possible to be able to be paid by the most amount of people, and most expensive possible so that you earn the highest amount of money. So, much more people than just the rich.

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BitchyWitchy68 t1_jdqj7rw wrote

That’s assuming that Capitalism plays fair, which it does not.

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Dziadzios t1_jdqd19r wrote

New thyroid that can make me lose weight? Sign me up!

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Imaginary_Passage431 t1_jdqdnxz wrote

Please we need artificial organs!!! You probably need them right now if you’re +30 like me. An artificial spine to prevent back pain, artificial eyes to not have hyper/hypometropia, artificial hair follicules for baldness, etc. we already have artificial teeth and most people prefer them.

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GMANTRONX t1_jdqm54c wrote

Did anyone ever watch Incorporated where even artificial hearts had a subscription model and one poor kid almost had their heart taken away by the corporation for using a hacked heart or something along that line?
Yeah....I believe we may be heading in that direction.

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Tenter5 t1_jdqrrdj wrote

I appreciate the optimizing but you should really look at all the problems that occur when using artificial hearts. There is a reason heart transplants are gold standard and artificial hearts are just used for bridging.

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TrespasseR_ t1_jdqvcio wrote

You say it can't get sick, but I'm sure nature will find a way

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merien_nl t1_jdr5oiu wrote

Plastic? Printed organs are also bio. The printing is to arrange the cells. We are nowhere near the self renewing properties of living tissue. Even your grandma's new hips wear out in 8 to 10 years.

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imperatrixofthevoid t1_jdro53i wrote

Printed organs made from cells and genetically engineered might be better than what we have. The body is a brilliantly complicated thing and it will be incredibly hard for us to make artifical organs as replacements because an organ is essentially a machine built of many tiny machines and the body has a lot of functions to clean and repair itself that a plastic organ simply wouldn't: macrophages that move withing the tissue, different types of nervous and sensory tissue that innervate different organs, the lymphatic system, etc. No artifical organs can top that right now.

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IndigoFenix t1_jdrocgb wrote

Imagine just replacing each of your organs when they die and eventually you just go full Tin Man.

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L_Cranston_Shadow t1_jdrt4hs wrote

Makes sense, especially with printed organs they can greatly reduce the risk of rejection.

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harderisbetter t1_jdtqcdq wrote

doubt it, organs have crazy shit like the heart has neurons in it, it's not just a pump

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aperocknroll1988 t1_jdtrqqq wrote

Made of plastic? Unlikely, but we might see replacement organs grown from our own cells someday...

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desi_guy11 t1_jdv6wqi wrote

> Reckon we'll see a time where we'll straight up get organs made of plastic that surpass the one's we're born with?

I read the title and assumed 'printing' meant creating with living organisms not plastic.

We are already seeing a lot more regenerating using stem cells and parts from Pigs and Baboons not Plastic.

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mi2h_N0t-r34l_ t1_je6wivc wrote

Correct but some people are allergic to scalpels... How quickly a body could transition from one material to another is a valuable quandary to wade through and whether the body would adjust to the new reality without issue is another entirely; if aging were not a problem, old men would out-compete young men in any dating pool as they would quickly recover from hormone deficiency and production issues...

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wizardstrikes2 t1_jdq6mpr wrote

Printed organs, especially the brain, are easily 100-200 years away from a technology standpoint. We will live on places other than the earth by the time this tech emerges if ever.

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_Hellrazor_ t1_jdqim1l wrote

How can you equate creating an artificial brain to something vastly more simple in comparison such as an organ? Yes they are both complex tasks but one is quite clearly unfathomably more difficult to accomplish than the other. I don’t think it’s unreasonable to think we’ll see printed organs aside from the brain within the next few decades

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wizardstrikes2 t1_jdrfkm1 wrote

Brains are an organ. I hope you are right with your guess because millions of people need them asap.

It is my guess they are 40-50 years away from printing skin and simple organs like heart, liver, bladder, etc and that will be 100-200 years later. My guess is never on a complex organ like the brain.

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iPisslosses t1_jdqbk04 wrote

In this domain the most exciting thing is neuromapping as it is the only thing which can bring us close to immortality. In my religion we believe that the soul is our conscious mind,as long as the brain is working we are alive. If we map our brain to a droid we are practically immortal as our consciousness is in a near immortal body

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TheRappingSquid OP t1_jdxn8qp wrote

I dunno about neuromapping- like, I'd obviously be for it, but it seems that the human brain is fucking COMPLICATED. Like, the only way that would be possible would be in a breakthrough with quantum computing. Not even to mention that it wouldn't be a continuation but a copy- I'd be more interested in replacing the other, less complicated parts of the body with machinery while maintaining the brain as is

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